

| 货号 | ARO-A11782 |
|---|---|
| 品牌 | ProteoGenix |
| 描述 |
Anti-Human OSBPL2 Polyclonal Antibody (ARO-A11782) is a rabbit polyclonal antibody detecting ORP-2, Oxysterol-binding protein-related protein 2, ORP2, OSBPL2, KIAA0772, OSBP-related protein 2 in ELISA, IHC, WB. Suitable for Human.
Highlights
|
| 种属反应性 | Human |
| 应用 | ELISA, IHC, WB |
| 宿主 | Rabbit |
| 克隆类型 | Polyclonal |
| 同种型 | IgG |
| 免疫原 | E. coli - derived recombinant Human OSBPL2 (Ala96-Asp325). |
| 靶标 | ORP-2, Oxysterol-binding protein-related protein 2, ORP2, OSBPL2, KIAA0772, OSBP-related protein 2 |
| 纯化方式 | Purified by antigen affinity column. |
| Accession号 | Q9H1P3 |
| 状态 | Liquid |
| 保存溶液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 背景 | Oxysterol-binding protein-related protein 2 (OSBPL2) is a ~55 kDa protein. Intracellular transport protein that binds sterols and phospholipids and mediates lipid transport between intracellular compartments. Increases plasma membrane cholesterol levels and decreases phosphatidylinositol-4,5-bisphosphate levels in the cell membrane. Binds phosphoinositides, such as phosphatidylinositol-4,5-bisphosphate. Exhibits strong binding to phosphatidic acid and weak binding to phosphatidylinositol 3-phosphate. Binds cholesterol, dehydroergosterol, 22(R)-hydroxycholesterol and 25-hydroxycholesterol (in vitro). 1. Wang, H. et al. (2019) Molecular cell 73, 458-473.e7. PMID: 30581148 2. Xu, Y. et al. (2001) The Journal of biological chemistry 276, 18407-14. PMID: 11279184 3. Suchanek, M. et al. (2007) The Biochemical journal 405, 473-80. PMID: 17428193 4. Hynynen, R. et al. (2009) Journal of lipid research 50, 1305-15. PMID: 19224871 |
| Note | For research use only. |

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