

| 货号 | HW706024 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 品牌 | abinScience | ||||||||
| 种属反应性 | Human, Mouse, Rat | ||||||||
| 应用 | ELISA, IHC, WB | ||||||||
| 宿主 | Rabbit | ||||||||
| 同种型 | IgG | ||||||||
| 克隆类型 | Polyclonal | ||||||||
| 免疫原 | E. coli - derived recombinant Human GDNF (Ser78-Ile211). | ||||||||
| 靶标 | hGDNF, Astrocyte-derived trophic factor, Glial cell line-derived neurotrophic factor, ATF, GDNF | ||||||||
| 纯化方式 | Purified by antigen affinity column. | ||||||||
| Accession号 | P39905 | ||||||||
| 状态 | Liquid | ||||||||
| 保存溶液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
||||||||
| 产品使用信息 |
| ||||||||
| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Glial cell line-derived neurotrophic factor (GDNF) is a ~23 kDa protein. Neurotrophic factor that enhances survival and morphological differentiation of dopaminergic neurons and increases their high-affinity dopamine uptake. Acts by binding to its coreceptor, GFRA1, leading to autophosphorylation and activation of the RET receptor. Involved in the development of the neural crest. 1. Lin, LF. et al. (1993) Science (New York, N.Y.) 260, 1130-2. PMID: 8493557 2. Cik, M. et al. (2000) The Journal of biological chemistry 275, 27505-12. PMID: 10829012 3. Goodman, KM. et al. (2014) Cell reports 8, 1894-1904. PMID: 25242331 4. Li, J. et al. (2019) eLife 8. PMID: 31535977 5. Yan, H. et al. (2004) Developmental biology 272, 118-33. PMID: 15242795 | ||||||||
| Note | For research use only. |

24小时产品查询

扫一扫关注我们

专属渠道经理