Anti-GDNF Polyclonal Antibody (HW706014)

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概述
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参考文献
产品说明书

概述

货号

HW706014

品牌

abinScience

描述

Anti-GDNF Polyclonal Antibody (HW706014) is a rabbit polyclonal antibody detecting GDNF in ELISA, IHC, WB. Suitable for Human, Mouse, and Rat.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

种属反应性

Human

应用

ELISA, IHC, WB

宿主

Rabbit

同种型

IgG

克隆类型

Polyclonal

免疫原

E. coli - derived recombinant Human GDNF (Ser78-Gly107).

靶标

hGDNF, Astrocyte-derived trophic factor, Glial cell line-derived neurotrophic factor, ATF, GDNF

纯化方式

Purified by antigen affinity column.

Accession号

P39905

状态

Liquid

保存溶液

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

背景

Glial cell line-derived neurotrophic factor (GDNF) is a ~23 kDa protein. Neurotrophic factor that enhances survival and morphological differentiation of dopaminergic neurons and increases their high-affinity dopamine uptake. Acts by binding to its coreceptor, GFRA1, leading to autophosphorylation and activation of the RET receptor. Involved in the development of the neural crest.

1. Lin, LF. et al. (1993) Science (New York, N.Y.) 260, 1130-2. PMID: 8493557

2. Cik, M. et al. (2000) The Journal of biological chemistry 275, 27505-12. PMID: 10829012

3. Goodman, KM. et al. (2014) Cell reports 8, 1894-1904. PMID: 25242331

4. Li, J. et al. (2019) eLife 8. PMID: 31535977

5. Yan, H. et al. (2004) Developmental biology 272, 118-33. PMID: 15242795

Note

For research use only.

图片

参考文献

产品说明书

Anti-GDNF Polyclonal Antibody.pdf

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

浓度

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-GDNF Polyclonal Antibody (HW706014)

概述

图片

参考文献

产品说明书

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重组蛋白

抗体

试剂盒

实验相关试剂

Anti-GDNF Polyclonal Antibody (HW706014)

概述

图片

参考文献

产品说明书

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