

| 货号 | HV570014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 品牌 | abinScience | ||||||||
| 种属反应性 | Human | ||||||||
| 应用 | ELISA, IHC, WB | ||||||||
| 宿主 | Rabbit | ||||||||
| 克隆类型 | Polyclonal | ||||||||
| 同种型 | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Human ABCB10 (Leu492-Ala738). | ||||||||
| 靶标 | M-ABC2, ABC transporter 10 protein, Mitochondrial ATP-binding cassette 2, ATP-binding cassette sub-family B member 10, mitochondrial, ABCB10, ATP-binding cassette transporter 10 | ||||||||
| 纯化方式 | Purified by antigen affinity column. | ||||||||
| Accession号 | Q9NRK6 | ||||||||
| 状态 | Liquid | ||||||||
| 保存溶液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
||||||||
| 产品使用信息 |
| ||||||||
| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | ATP-binding cassette sub-family B member 10, mitochondrial (ABCB10) is a ~79 kDa protein. ATP-dependent transporter located in the mitochondrial inner membrane that catalyzes the export of biliverdin from the mitochondrial matrix, and plays a crucial role in hemoglobin synthesis and antioxidative stress. Participates in the early step of the heme biosynthetic process during insertion of iron into protoporphyrin IX (PPIX). Involved in the stabilization of the iron transporter mitoferrin-1/SLC25A37. In addition may be involved in mitochondrial unfolded protein response (UPRmt) signaling pathway, although ABCB10 probably does not participate in peptide export from mitochondria. 1. Tang, L. et al. (2012) British journal of haematology 157, 151-4. PMID: 22085049 2. Yano, M. (2017) Biochemical and biophysical research communications 486, 465-469. PMID: 28315685 3. Seguin, A. et al. (2017) The Journal of biological chemistry 292, 16284-16299. PMID: 28808058 4. Shum, M. et al. (2021) Science translational medicine 13. PMID: 34011630 5. Cao, S. et al. (2023) Nature communications 14, 2030. PMID: 37041204 | ||||||||
| Note | For research use only. |

24小时产品查询

扫一扫关注我们

专属渠道经理