Anti-NDC80/HEC1 Polyclonal Antibody (HT177014)

价格:

规格：

50ug
100ug

数量：

一键复制产品信息

概述
图片
参考文献
产品说明书

HT177014

abinScience

种属反应性

Human

ELISA, IHC, WB

Rabbit

Polyclonal

E. coli - derived recombinant Human NDC80/HEC1 (Pro290-Glu642).

HEC1, Kinetochore protein Hec1, HsHec1, HEC, Kinetochore protein NDC80 homolog, Kinetochore-associated protein 2, NDC80, Highly expressed in cancer protein, Retinoblastoma-associated protein HEC, KNTC2

Purified by antigen affinity column.

Accession号

O14777

Liquid

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Kinetochore protein NDC80 homolog (HEC1) is a ~73 kDa protein. Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity. Required for kinetochore integrity and the organization of stable microtubule binding sites in the outer plate of the kinetochore. The NDC80 complex synergistically enhances the affinity of the SKA1 complex for microtubules and may allow the NDC80 complex to track depolymerizing microtubules. Plays a role in chromosome congression and is essential for the end-on attachment of the kinetochores to spindle microtubules.

1. Martin-Lluesma, S. et al. (2002) Science (New York, N.Y.) 297, 2267-70. PMID: 12351790

2. DeLuca, JG. et al. (2003) Current biology : CB 13, 2103-9. PMID: 14654001

3. Bharadwaj, R. et al. (2004) The Journal of biological chemistry 279, 13076-85. PMID: 14699129

4. Joseph, J. et al. (2004) Current biology : CB 14, 611-7. PMID: 15062103

5. Stucke, VM. et al. (2004) Chromosoma 113, 1-15. PMID: 15235793

6. Meraldi, P. et al. (2004) Developmental cell 7, 45-60. PMID: 15239953

7. DeLuca, JG. et al. (2005) Molecular biology of the cell 16, 519-31. PMID: 15548592

8. Lin, YT. et al. (2006) Oncogene 25, 6901-14. PMID: 16732327

9. Zhao, G. et al. (2019) The Journal of biological chemistry 294, 576-592. PMID: 30409912

10. Chen, Y. et al. (1997) Molecular and cellular biology 17, 6049-56. PMID: 9315664

For research use only.

产品说明书

Anti-NDC80/HEC1 Polyclonal Antibody.pdf

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

分子量 *

g/mol

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

C₁ (起始浓度)

V₁ (起始体积)

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-NDC80/HEC1 Polyclonal Antibody (HT177014)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-NDC80/HEC1 Polyclonal Antibody (HT177014)

概述

图片

参考文献

产品说明书

相关产品推荐

获取报价