Anti-Human NDC80/HEC1 Recombinant Antibody (9G3) (HT177013)

价格:

规格：

50ug
100ug
1mg

数量：

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概述
图片
参考文献
产品说明书

HT177013

abinScience

种属反应性

Human

FCM, ICC, IF, IP, WB

IgG2a, kappa

Kinetochore protein NDC80 homolog, Highly expressed in cancer protein, Kinetochore protein Hec1, HsHec1, Kinetochore-associated protein 2, Retinoblastoma-associated protein HEC, NDC80, HEC, HEC1, KNTC2

内毒素水平

Please contact with the lab for this information.

>95% as determined by SDS-PAGE.

Protein A/G purified from cell culture supernatant.

Accession号

O14777

Anti-Human NDC80/HEC1 Antibody (9G3) (abinScience Cat# HT177013, RRID:AB_3729529)

Liquid

0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
WB	1:500-1:2000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Kinetochore protein NDC80 homolog (HEC1) is a ~73 kDa protein. Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity. Required for kinetochore integrity and the organization of stable microtubule binding sites in the outer plate of the kinetochore. The NDC80 complex synergistically enhances the affinity of the SKA1 complex for microtubules and may allow the NDC80 complex to track depolymerizing microtubules. Plays a role in chromosome congression and is essential for the end-on attachment of the kinetochores to spindle microtubules.

1. Martin-Lluesma, S. et al. (2002) Science (New York, N.Y.) 297, 2267-70. PMID: 12351790

2. DeLuca, JG. et al. (2003) Current biology : CB 13, 2103-9. PMID: 14654001

3. Bharadwaj, R. et al. (2004) The Journal of biological chemistry 279, 13076-85. PMID: 14699129

4. Joseph, J. et al. (2004) Current biology : CB 14, 611-7. PMID: 15062103

5. Stucke, VM. et al. (2004) Chromosoma 113, 1-15. PMID: 15235793

6. Meraldi, P. et al. (2004) Developmental cell 7, 45-60. PMID: 15239953

7. DeLuca, JG. et al. (2005) Molecular biology of the cell 16, 519-31. PMID: 15548592

8. Lin, YT. et al. (2006) Oncogene 25, 6901-14. PMID: 16732327

9. Zhao, G. et al. (2019) The Journal of biological chemistry 294, 576-592. PMID: 30409912

10. Chen, Y. et al. (1997) Molecular and cellular biology 17, 6049-56. PMID: 9315664

For research use only.

SDS-PAGE

SDS-PAGE for Anti-Human NDC80/HEC1 Antibody (9G3)

产品说明书

Anti-Human NDC80/HEC1 Recombinant Antibody (9G3).pdf

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

分子量 *

g/mol

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

C₁ (起始浓度)

V₁ (起始体积)

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human NDC80/HEC1 Recombinant Antibody (9G3) (HT177013)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human NDC80/HEC1 Recombinant Antibody (9G3) (HT177013)

概述

图片

参考文献

产品说明书

相关产品推荐

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