Anti-Human Thrombopoietin R/Tpo R Polyclonal Antibody (HW601014)

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HW601014

abinScience

种属反应性

Human

ELISA, IHC, WB

Rabbit

Polyclonal

E. coli - derived recombinant Human CD110/MPL (Ser311-Gln460).

TPO-R, TPOR, Thrombopoietin receptor, MPL, Myeloproliferative leukemia protein, Proto-oncogene c-Mpl, CD110

Purified by antigen affinity column.

Accession号

P40238

Liquid

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Thrombopoietin receptor (CD110/MPL) is a ~71 kDa protein. Receptor for thrombopoietin that regulates hematopoietic stem cell renewal, megakaryocyte differentiation, and platelet formation. Upon activation by THPO, induces rapid tyrosine phosphorylation and activation of JAK2, providing docking sites for many signaling proteins such as STAT5, SHIP/INPP5D, GRB2, SOS1 and PI3K. In turn, These signaling cascades lead to the proliferation, survival, and differentiation of megakaryocytes, ultimately leading to increased platelet production.

1. Royer, Y. et al. (2005) The Journal of biological chemistry 280, 27251-61. PMID: 15899890

2. Tsutsumi, N. et al. (2023) Cell 186, 4189-4203.e22. PMID: 37633268

For research use only.

产品说明书

Anti-Human Thrombopoietin R/Tpo R Polyclonal Antibody.pdf

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

分子量 *

g/mol

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

C₁ (起始浓度)

V₁ (起始体积)

C₂ (终浓度)

V₂ (终体积)

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实验相关试剂

Anti-Human Thrombopoietin R/Tpo R Polyclonal Antibody (HW601014)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human Thrombopoietin R/Tpo R Polyclonal Antibody (HW601014)

概述

图片

参考文献

产品说明书

相关产品推荐

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