Anti-VDR Polyclonal Antibody (HY304014)

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50ug
100ug

数量：

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概述
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参考文献
产品说明书

HY304014

abinScience

种属反应性

Human, Rat

ELISA, IHC, WB

Rabbit

Polyclonal

E. coli - derived recombinant Human VDR (Met272-Ser427).

VDR, Vitamin D3 receptor, 1, 25-dihydroxyvitamin D3 receptor, NR1I1, Nuclear receptor subfamily 1 group I member 1

Purified by antigen affinity column.

Accession号

P11473

Liquid

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Vitamin D3 receptor (VDR) is a ~48 kDa protein. Nuclear receptor for calcitriol, the active form of vitamin D3 which mediates the action of this vitamin on cells. Enters the nucleus upon vitamin D3 binding where it forms heterodimers with the retinoid X receptor/RXR. The VDR-RXR heterodimers bind to specific response elements on DNA and activate the transcription of vitamin D3-responsive target genes. Plays a central role in calcium homeostasis. Also functions as a receptor for the secondary bile acid lithocholic acid (LCA) and its metabolites.

1. Rochel, N. et al. (2000) Molecular cell 5, 173-9. PMID: 10678179

2. Eelen, G. et al. (2005) Molecular pharmacology 67, 1566-73. PMID: 15728261

3. Hourai, S. et al. (2006) Journal of medicinal chemistry 49, 5199-205. PMID: 16913708

4. Tamura, M. et al. (2017) Scientific reports 7, 5102. PMID: 28698609

5. Tsai, JM. et al. (2023) Molecular cell 83, 2753-2767.e10. PMID: 37478846

6. Makishima, M. et al. (2002) Science (New York, N.Y.) 296, 1313-6. PMID: 12016314

7. Hashimoto, N. et al. (2020) Kidney international 97, 1164-1180. PMID: 32354638

For research use only.

产品说明书

Anti-VDR Polyclonal Antibody.pdf

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

分子量 *

g/mol

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

C₁ (起始浓度)

V₁ (起始体积)

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-VDR Polyclonal Antibody (HY304014)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-VDR Polyclonal Antibody (HY304014)

概述

图片

参考文献

产品说明书

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