Anti-CDC20 Polyclonal Antibody (HC333014)

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规格：

50ug
100ug

数量：

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概述
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参考文献
产品说明书

HC333014

abinScience

种属反应性

Human, Mouse, Rat

ELISA, IHC, WB

Rabbit

Polyclonal

E. coli - derived recombinant Human CDC20 (Gln218-Arg471).

Cell division cycle protein 20 homolog, p55CDC, CDC20

Purified by antigen affinity column.

Accession号

Q12834

Liquid

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Cell division cycle protein 20 homolog (CDC20) is a ~54 kDa protein. Substrate-specific adapter of the anaphase promoting complex/cyclosome (APC/C) complex that confers substrate specificity by binding to substrates and targeting them to the APC/C complex for ubiquitination and degradation. Recognizes and binds the destruction box (D box) on protein substrates. Involved in the metaphase/anaphase transition of cell cycle. Is regulated by MAD2L1: in metaphase the MAD2L1-CDC20-APC/C ternary complex is inactive and in anaphase the CDC20-APC/C binary complex is active in degrading substrates. The CDC20-APC/C complex positively regulates the formation of synaptic vesicle clustering at active zone to the presynaptic membrane in postmitotic neurons.

1. Fang, G. et al. (1998) Molecular cell 2, 163-71. PMID: 9734353

2. Lin, Z. et al. (2015) Cell discovery 1, 15028-. PMID: 27030811

3. Choppara, S. et al. (2018) Proceedings of the National Academy of Sciences of the United States of America 115, 998-1003. PMID: 29343641

4. Zhao, L. et al. (2020) Protein & cell 11, 921-927. PMID: 32666501

5. Kramer, ER. et al. (1998) Current biology : CB 8, 1207-10. PMID: 9811605

6. Fang, G. et al. (1998) Genes & development 12, 1871-83. PMID: 9637688

For research use only.

产品说明书

Anti-CDC20 Polyclonal Antibody.pdf

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

分子量 *

g/mol

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

C₁ (起始浓度)

V₁ (起始体积)

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-CDC20 Polyclonal Antibody (HC333014)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-CDC20 Polyclonal Antibody (HC333014)

概述

图片

参考文献

产品说明书

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