Anti-ADRA1A Polyclonal Antibody (HW676014)

价格:

规格：

50ug
100ug

数量：

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概述
图片
参考文献
产品说明书

HW676014

abinScience

种属反应性

Human

ELISA, IHC, WB

Rabbit

Polyclonal

E. coli - derived recombinant Human ADRA1A (Ser330-Val466).

ADRA1C, ADRA1A, Alpha-1A adrenoreceptor, Alpha-1C adrenergic receptor, Alpha-adrenergic receptor 1c, Alpha-1A adrenoceptor, Alpha-1A adrenergic receptor

Purified by antigen affinity column.

Accession号

P35348

Liquid

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Alpha-1A adrenergic receptor (ADRA1A) is a ~51 kDa protein. Alpha-1 adrenergic receptors are G protein-coupled receptors for catecholamines that signal through the G(q) family of G proteins, including G(q) and G(11). Upon activation, they stimulate the phosphatidylinositol-calcium second messenger pathway, leading to calcium release from intracellular stores and activation of protein kinase C. ADRA1A binds the catecholamine ligands norepinephrine and epinephrine. Can also couple to G(14) protein. Nuclear ADRA1A forms heterooligomers with ADRA1B to regulate phenylephrine(PE)-stimulated ERK signaling in cardiac myocytes.

1. Su, M. et al. (2023) Nature communications 14, 4819. PMID: 37563160

2. Wright, CD. et al. (2008) Circulation research 103, 992-1000. PMID: 18802028

3. Schwinn, DA. et al. (1995) The Journal of pharmacology and experimental therapeutics 272, 134-42. PMID: 7815325

4. Weinberg, DH. et al. (1994) Biochemical and biophysical research communications 201, 1296-304. PMID: 8024574

5. Forray, C. et al. (1994) Molecular pharmacology 45, 703-8. PMID: 8183249

6. Shibata, K. et al. (1996) British journal of pharmacology 118, 1403-8. PMID: 8832064

7. Wright, CD. et al. (2012) Cellular signalling 24, 794-802. PMID: 22120526

8. Ogata, T. et al. (2014) Proceedings of the National Academy of Sciences of the United States of America 111, 3811-6. PMID: 24567387

For research use only.

产品说明书

Anti-ADRA1A Polyclonal Antibody.pdf

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

分子量 *

g/mol

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

C₁ (起始浓度)

V₁ (起始体积)

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-ADRA1A Polyclonal Antibody (HW676014)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-ADRA1A Polyclonal Antibody (HW676014)

概述

图片

参考文献

产品说明书

相关产品推荐

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