Anti-STIM1 Polyclonal Antibody (HC687014)

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50ug
100ug

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概述
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参考文献
产品说明书

HC687014

abinScience

种属反应性

Human, Mouse, Rat

ELISA, IHC, WB

Rabbit

Polyclonal

E. coli - derived recombinant Human STIM1 (Ser28-Leu211).

STIM1, Stromal interaction molecule 1, GOK

Purified by antigen affinity column.

Accession号

Q13586

Liquid

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Stromal interaction molecule 1 (STIM1) is a ~77 kDa protein. Acts as a Ca(2+) sensor that gates two major inward rectifying Ca(2+) channels at the plasma membrane: Ca(2+) release-activated Ca(2+) (CRAC) channels and arachidonate-regulated Ca(2+)-selective (ARC) channels. Plays a role in mediating store-operated Ca(2+) entry (SOCE), a Ca(2+) influx following depletion of intracellular Ca(2+) stores. Upon Ca(2+) depletion, translocates from the endoplasmic reticulum to the plasma membrane where it activates CRAC channel pore-forming subunits ORA1, ORA2 and ORAI3 to generate sustained and oscillatory Ca(2+) entry. Involved in enamel formation.

1. Roos, J. et al. (2005) The Journal of cell biology 169, 435-45. PMID: 15866891

2. Liou, J. et al. (2005) Current biology : CB 15, 1235-41. PMID: 16005298

3. Zhang, SL. et al. (2005) Nature 437, 902-5. PMID: 16208375

4. Spassova, MA. et al. (2006) Proceedings of the National Academy of Sciences of the United States of America 103, 4040-5. PMID: 16537481

5. Peinelt, C. et al. (2006) Nature cell biology 8, 771-3. PMID: 16733527

6. Soboloff, J. et al. (2006) The Journal of biological chemistry 281, 20661-20665. PMID: 16766533

7. Mercer, JC. et al. (2006) The Journal of biological chemistry 281, 24979-90. PMID: 16807233

8. Stathopulos, PB. et al. (2008) Cell 135, 110-22. PMID: 18854159

9. Yuan, JP. et al. (2009) Nature cell biology 11, 337-43. PMID: 19182790

10. Park, CY. et al. (2009) Cell 136, 876-90. PMID: 19249086

For research use only.

产品说明书

Anti-STIM1 Polyclonal Antibody.pdf

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

分子量 *

g/mol

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

C₁ (起始浓度)

V₁ (起始体积)

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-STIM1 Polyclonal Antibody (HC687014)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-STIM1 Polyclonal Antibody (HC687014)

概述

图片

参考文献

产品说明书

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