Anti-ARNT/HIF1-beta Polyclonal Antibody (HB629014)

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50ug
100ug

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HB629014

abinScience

种属反应性

Human, Mouse, Rat

ELISA, IHC, WB

Rabbit

Polyclonal

E. coli - derived recombinant Human ARNT/HIF1-beta (Thr361-Val464).

ARNT, Dioxin receptor, nuclear translocator, ARNT protein, bHLHe2, BHLHE2, Aryl hydrocarbon receptor nuclear translocator, Hypoxia-inducible factor 1-beta, HIF1-beta, Class E basic helix-loop-helix protein 2, HIF-1-beta

Purified by antigen affinity column.

Accession号

P27540

Liquid

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Aryl hydrocarbon receptor nuclear translocator (ARNT/HIF1-beta) is a ~86 kDa protein. Required for activity of the AHR. Upon ligand binding, AHR translocates into the nucleus, where it heterodimerizes with ARNT and induces transcription by binding to xenobiotic response elements (XRE). Not required for the ligand-binding subunit to translocate from the cytosol to the nucleus after ligand binding. The complex initiates transcription of genes involved in the regulation of a variety of biological processes, including angiogenesis, hematopoiesis, drug and lipid metabolism, cell motility and immune modulation (Probable). The heterodimer binds to core DNA sequence 5'-TACGTG-3' within the hypoxia response element (HRE) of target gene promoters and functions as a transcriptional regulator of the adaptive response to hypoxia.

1. Haidar, R. et al. (2021) Scientific reports 11, 18194. PMID: 34521881

2. Seok, SH. et al. (2017) Proceedings of the National Academy of Sciences of the United States of America 114, 5431-5436. PMID: 28396409

For research use only.

产品说明书

Anti-ARNT/HIF1-beta Polyclonal Antibody.pdf

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

分子量 *

g/mol

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

C₁ (起始浓度)

V₁ (起始体积)

C₂ (终浓度)

V₂ (终体积)

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Anti-ARNT/HIF1-beta Polyclonal Antibody (HB629014)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-ARNT/HIF1-beta Polyclonal Antibody (HB629014)

概述

图片

参考文献

产品说明书

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