

| 货号 | HV236014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 品牌 | abinScience | ||||||||
| 种属反应性 | Human | ||||||||
| 应用 | ELISA, IHC, WB | ||||||||
| 宿主 | Rabbit | ||||||||
| 同种型 | IgG | ||||||||
| 克隆类型 | Polyclonal | ||||||||
| 免疫原 | E. coli - derived recombinant Human LYVE1 (Arg26-Ser131). | ||||||||
| 靶标 | Cell surface retention sequence-binding protein 1, XLKD1, LYVE-1, Hyaluronic acid receptor, Extracellular link domain-containing protein 1, CRSBP-1, LYVE1, CRSBP1, HAR, Lymphatic vessel endothelial hyaluronic acid receptor 1 | ||||||||
| 纯化方式 | Purified by antigen affinity column. | ||||||||
| Accession号 | Q9Y5Y7 | ||||||||
| 状态 | Liquid | ||||||||
| 保存溶液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| 产品使用信息 |
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| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Lymphatic vessel endothelial hyaluronic acid receptor 1 (LYVE1) is a ~35 kDa protein. Ligand-specific transporter trafficking between intracellular organelles (TGN) and the plasma membrane. Plays a role in autocrine regulation of cell growth mediated by growth regulators containing cell surface retention sequence binding (CRS). May act as a hyaluronan (HA) transporter, either mediating its uptake for catabolism within lymphatic endothelial cells themselves, or its transport into the lumen of afferent lymphatic vessels for subsequent re-uptake and degradation in lymph nodes. Binds to pericelluar hyaluronan matrices deposited on the surface of leukocytes and facilitates cell adhesion and migration through lymphatic endothelium. 1. Banerji, S. et al. (1999) The Journal of cell biology 144, 789-801. PMID: 10037799 2. Lawrance, W. et al. (2016) The Journal of biological chemistry 291, 8014-30. PMID: 26823460 | ||||||||
| Note | For research use only. |

Western blot analysis was performed using anti-LYVE1 polyclonal antibody at 1ug/mL on various samples.
Lane 1: Rat brain lysate



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