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Anti-Human LYVE1 Polyclonal Antibody (ARO-A11224)

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概述
货号ARO-A11224
品牌ProteoGenix
描述
Anti-Human LYVE1 Polyclonal Antibody (ARO-A11224) is a rabbit polyclonal antibody detecting Cell surface retention sequence-binding protein 1, XLKD1, LYVE-1, Hyaluronic acid receptor, Extracellular link domain-containing protein 1, CRSBP-1, LYVE1, CRSBP1, HAR, Lymphatic vessel endothelial hyaluronic acid receptor 1 in ELISA, IHC, WB. Suitable for Human.
Highlights
  • Affinity Purified — Minimal background and high purity for reliable results.
  • Multi-Application — Validated across multiple applications.
种属反应性Human
应用ELISA, IHC, WB
宿主Rabbit
同种型IgG
克隆类型Polyclonal
免疫原E. coli - derived recombinant Human LYVE1 (Arg26-Ser131).
靶标Cell surface retention sequence-binding protein 1, XLKD1, LYVE-1, Hyaluronic acid receptor, Extracellular link domain-containing protein 1, CRSBP-1, LYVE1, CRSBP1, HAR, Lymphatic vessel endothelial hyaluronic acid receptor 1
纯化方式Purified by antigen affinity column.
Accession号Q9Y5Y7
状态Liquid
保存溶液 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景

Lymphatic vessel endothelial hyaluronic acid receptor 1 (LYVE1) is a ~35 kDa protein. Ligand-specific transporter trafficking between intracellular organelles (TGN) and the plasma membrane. Plays a role in autocrine regulation of cell growth mediated by growth regulators containing cell surface retention sequence binding (CRS). May act as a hyaluronan (HA) transporter, either mediating its uptake for catabolism within lymphatic endothelial cells themselves, or its transport into the lumen of afferent lymphatic vessels for subsequent re-uptake and degradation in lymph nodes. Binds to pericelluar hyaluronan matrices deposited on the surface of leukocytes and facilitates cell adhesion and migration through lymphatic endothelium.

1. Banerji, S. et al. (1999) The Journal of cell biology 144, 789-801. PMID: 10037799
2. Lawrance, W. et al. (2016) The Journal of biological chemistry 291, 8014-30. PMID: 26823460
NoteFor research use only.
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参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项，自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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