Anti-Human AMOTL2/LCCP Polyclonal Antibody (HP046014)

价格:

规格：

50ug
100ug

数量：

一键复制产品信息

概述
图片
参考文献
产品说明书

HP046014

abinScience

种属反应性

Human, Mouse, Rat

ELISA, IHC, WB

Rabbit

Polyclonal

E. coli - derived recombinant Human AMOTL2/LCCP (Ser540-Asp653).

LCCP, AMOTL2, Angiomotin-like protein 2, Leman coiled-coil protein, KIAA0989

Purified by antigen affinity column.

Accession号

Q9Y2J4

Liquid

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Angiomotin-like protein 2 (AMOTL2/LCCP) is a ~85 kDa protein. Regulates the translocation of phosphorylated SRC to peripheral cell-matrix adhesion sites. Required for proper architecture of actin filaments. Plays a role in coupling actin fibers to cell junctions in endothelial cells and is therefore required for correct endothelial cell morphology via facilitating transcellular transmission of mechanical force resulting in endothelial cell elongation. Required for the anchoring of radial actin fibers to CDH1 junction complexes at the cell membrane which facilitates organization of radial actin fiber structure and cellular response to contractile forces. This contributes to maintenance of cell area, size, shape, epithelial sheet organization and trophectoderm cell properties that facilitate blastocyst zona hatching.

1. Hildebrand, S. et al. (2017) Scientific reports 7, 9540. PMID: 28842668

2. Hwang, D. et al. (2021) Life science alliance 4. PMID: 34404733

3. Huang, H. et al. (2007) Development (Cambridge, England) 134, 979-88. PMID: 17293535

4. Zhao, B. et al. (2011) Genes & development 25, 51-63. PMID: 21205866

5. Kim, M. et al. (2016) EMBO reports 17, 64-78. PMID: 26598551

6. Lucci, V. et al. (2013) Gene 529, 300-6. PMID: 23911299

7. Proszynski, TJ. et al. (2013) Journal of cell science 126, 2225-35. PMID: 23525008

For research use only.

产品说明书

Anti-Human AMOTL2/LCCP Polyclonal Antibody.pdf

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

分子量 *

g/mol

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

C₁ (起始浓度)

V₁ (起始体积)

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human AMOTL2/LCCP Polyclonal Antibody (HP046014)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human AMOTL2/LCCP Polyclonal Antibody (HP046014)

概述

图片

参考文献

产品说明书

相关产品推荐

获取报价