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Anti-Human AMOTL2/LCCP Polyclonal Antibody (ARO-A11193)

概述
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参考文献

概述

货号	ARO-A11193
品牌	ProteoGenix
描述	Anti-Human AMOTL2/LCCP Polyclonal Antibody (ARO-A11193) is a rabbit polyclonal antibody detecting LCCP, AMOTL2, Angiomotin-like protein 2, Leman coiled-coil protein, KIAA0989 in ELISA, IHC, WB. Suitable for Human. Highlights Affinity Purified — Minimal background and high purity for reliable results. Multi-Application — Validated across multiple applications.
种属反应性	Human
应用	ELISA, IHC, WB
宿主	Rabbit
克隆类型	Polyclonal
同种型	IgG
免疫原	E. coli - derived recombinant Human AMOTL2/LCCP (Ser540-Asp653).
靶标	LCCP, AMOTL2, Angiomotin-like protein 2, Leman coiled-coil protein, KIAA0989
纯化方式	Purified by antigen affinity column.
Accession号	Q9Y2J4
状态	Liquid
保存溶液	0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景	Angiomotin-like protein 2 (AMOTL2/LCCP) is a ~85 kDa protein. Regulates the translocation of phosphorylated SRC to peripheral cell-matrix adhesion sites. Required for proper architecture of actin filaments. Plays a role in coupling actin fibers to cell junctions in endothelial cells and is therefore required for correct endothelial cell morphology via facilitating transcellular transmission of mechanical force resulting in endothelial cell elongation. Required for the anchoring of radial actin fibers to CDH1 junction complexes at the cell membrane which facilitates organization of radial actin fiber structure and cellular response to contractile forces. This contributes to maintenance of cell area, size, shape, epithelial sheet organization and trophectoderm cell properties that facilitate blastocyst zona hatching. 1. Hildebrand, S. et al. (2017) Scientific reports 7, 9540. PMID: 28842668 2. Hwang, D. et al. (2021) Life science alliance 4. PMID: 34404733 3. Huang, H. et al. (2007) Development (Cambridge, England) 134, 979-88. PMID: 17293535 4. Zhao, B. et al. (2011) Genes & development 25, 51-63. PMID: 21205866 5. Kim, M. et al. (2016) EMBO reports 17, 64-78. PMID: 26598551 6. Lucci, V. et al. (2013) Gene 529, 300-6. PMID: 23911299 7. Proszynski, TJ. et al. (2013) Journal of cell science 126, 2225-35. PMID: 23525008
Note	For research use only.

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参考文献

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

=

浓度

×

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

×

V₁ (起始体积)

=

工作液

C₂ (终浓度)

×

V₂ (终体积)

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Anti-Human AMOTL2/LCCP Polyclonal Antibody

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