

| 货号 | HP612014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 品牌 | abinScience | ||||||||
| 种属反应性 | Human, Mouse, Rat | ||||||||
| 应用 | ELISA, IHC, WB | ||||||||
| 宿主 | Rabbit | ||||||||
| 克隆类型 | Polyclonal | ||||||||
| 同种型 | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Human PACSIN2 (Ser425-Gln486). | ||||||||
| 靶标 | Protein kinase C and casein kinase substrate in neurons protein 2, SdpII, Syndapin-2, Syndapin-II, PACSIN2 | ||||||||
| 纯化方式 | Purified by antigen affinity column. | ||||||||
| Accession号 | Q9UNF0 | ||||||||
| 状态 | Liquid | ||||||||
| 保存溶液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
||||||||
| 产品使用信息 |
| ||||||||
| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Protein kinase C and casein kinase substrate in neurons protein 2 (PACSIN2) is a ~55 kDa protein. Regulates the morphogenesis and endocytosis of caveolae. Lipid-binding protein that is able to promote the tubulation of the phosphatidic acid-containing membranes it preferentially binds. Plays a role in intracellular vesicle-mediated transport. Involved in the endocytosis of cell-surface receptors like the EGF receptor, contributing to its internalization in the absence of EGF stimulus. Essential for endothelial organization in sprouting angiogenesis, modulates CDH5-based junctions. 1. de Kreuk, BJ. et al. (2011) Journal of cell science 124, 2375-88. PMID: 21693584 2. de Kreuk, BJ. et al. (2012) The Journal of biological chemistry 287, 43438-53. PMID: 23129763 3. Goh, SL. et al. (2012) PloS one 7, e51628. PMID: 23236520 4. Giridharan, SS. et al. (2013) Molecular biology of the cell 24, 1776-90, S1-15. PMID: 23596323 | ||||||||
| Note | For research use only. |

24小时产品查询

扫一扫关注我们

专属渠道经理