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Anti-Human PACSIN2 Polyclonal Antibody (ARO-A11177)

概述
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参考文献

概述

货号	ARO-A11177
品牌	ProteoGenix
描述	Anti-Human PACSIN2 Polyclonal Antibody (ARO-A11177) is a rabbit polyclonal antibody detecting Protein kinase C and casein kinase substrate in neurons protein 2, SdpII, Syndapin-2, Syndapin-II, PACSIN2 in ELISA, IHC, WB. Suitable for Human. Highlights Affinity Purified — Minimal background and high purity for reliable results. Multi-Application — Validated across multiple applications.
种属反应性	Human
应用	ELISA, IHC, WB
宿主	Rabbit
克隆类型	Polyclonal
同种型	IgG
免疫原	E. coli - derived recombinant Human PACSIN2 (Ser425-Gln486).
靶标	Protein kinase C and casein kinase substrate in neurons protein 2, SdpII, Syndapin-2, Syndapin-II, PACSIN2
纯化方式	Purified by antigen affinity column.
Accession号	Q9UNF0
状态	Liquid
保存溶液	0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景	Protein kinase C and casein kinase substrate in neurons protein 2 (PACSIN2) is a ~55 kDa protein. Regulates the morphogenesis and endocytosis of caveolae. Lipid-binding protein that is able to promote the tubulation of the phosphatidic acid-containing membranes it preferentially binds. Plays a role in intracellular vesicle-mediated transport. Involved in the endocytosis of cell-surface receptors like the EGF receptor, contributing to its internalization in the absence of EGF stimulus. Essential for endothelial organization in sprouting angiogenesis, modulates CDH5-based junctions. 1. de Kreuk, BJ. et al. (2011) Journal of cell science 124, 2375-88. PMID: 21693584 2. de Kreuk, BJ. et al. (2012) The Journal of biological chemistry 287, 43438-53. PMID: 23129763 3. Goh, SL. et al. (2012) PloS one 7, e51628. PMID: 23236520 4. Giridharan, SS. et al. (2013) Molecular biology of the cell 24, 1776-90, S1-15. PMID: 23596323
Note	For research use only.

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参考文献

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

=

浓度

×

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

×

V₁ (起始体积)

=

工作液

C₂ (终浓度)

×

V₂ (终体积)

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Anti-Human PACSIN2 Polyclonal Antibody

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