

| 货号 | HP154014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 品牌 | abinScience | ||||||||
| 种属反应性 | Human, Mouse | ||||||||
| 应用 | ELISA, IHC, WB | ||||||||
| 宿主 | Rabbit | ||||||||
| 克隆类型 | Polyclonal | ||||||||
| 同种型 | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Human RANBP9 (Ser176-Gly330). | ||||||||
| 靶标 | RanBP7, RanBPM, RanBP9, Ran-binding protein 9, Ran-binding protein M, BPM90, RANBP9, BPM-L, RANBPM | ||||||||
| 纯化方式 | Purified by antigen affinity column. | ||||||||
| Accession号 | Q96S59 | ||||||||
| 状态 | Liquid | ||||||||
| 保存溶液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| 产品使用信息 |
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| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Ran-binding protein 9 (RANBP9) is a ~77 kDa protein. May act as scaffolding protein, and as adapter protein to couple membrane receptors to intracellular signaling pathways (Probable). Acts as a mediator of cell spreading and actin cytoskeleton rearrangement. Core component of the CTLH E3 ubiquitin-protein ligase complex that selectively accepts ubiquitin from UBE2H and mediates ubiquitination and subsequent proteasomal degradation of the transcription factor HBP1. May be involved in signaling of ITGB2/LFA-1 and other integrins. Enhances HGF-MET signaling by recruiting Sos and activating the Ras pathway. 1. Valiyaveettil, M. et al. (2008) The Journal of cell biology 182, 727-39. PMID: 18710924 2. Lampert, F. et al. (2018) eLife 7. PMID: 29911972 3. Denti, S. et al. (2004) The Journal of biological chemistry 279, 13027-34. PMID: 14722085 4. Wang, D. et al. (2002) The Journal of biological chemistry 277, 36216-22. PMID: 12147692 5. Rao, MA. et al. (2002) The Journal of biological chemistry 277, 48020-7. PMID: 12361945 6. Harada, N. et al. (2008) Biochemical and biophysical research communications 368, 121-5. PMID: 18222118 7. Kramer, S. et al. (2005) Oncogene 24, 938-44. PMID: 15558019 | ||||||||
| Note | For research use only. |

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