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Anti-Human RANBP9 Polyclonal Antibody (ARO-A11166)

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概述
货号ARO-A11166
品牌ProteoGenix
描述
Anti-Human RANBP9 Polyclonal Antibody (ARO-A11166) is a rabbit polyclonal antibody detecting RanBP7, RanBPM, RanBP9, Ran-binding protein 9, Ran-binding protein M, BPM90, RANBP9, BPM-L, RANBPM in ELISA, IHC, WB. Suitable for Human.
Highlights
  • Affinity Purified — Minimal background and high purity for reliable results.
  • Multi-Application — Validated across multiple applications.
种属反应性Human
应用ELISA, IHC, WB
宿主Rabbit
克隆类型Polyclonal
同种型IgG
免疫原E. coli - derived recombinant Human RANBP9 (Ser176-Gly330).
靶标RanBP7, RanBPM, RanBP9, Ran-binding protein 9, Ran-binding protein M, BPM90, RANBP9, BPM-L, RANBPM
纯化方式Purified by antigen affinity column.
Accession号Q96S59
状态Liquid
保存溶液 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景

Ran-binding protein 9 (RANBP9) is a ~77 kDa protein. May act as scaffolding protein, and as adapter protein to couple membrane receptors to intracellular signaling pathways (Probable). Acts as a mediator of cell spreading and actin cytoskeleton rearrangement. Core component of the CTLH E3 ubiquitin-protein ligase complex that selectively accepts ubiquitin from UBE2H and mediates ubiquitination and subsequent proteasomal degradation of the transcription factor HBP1. May be involved in signaling of ITGB2/LFA-1 and other integrins. Enhances HGF-MET signaling by recruiting Sos and activating the Ras pathway.

1. Valiyaveettil, M. et al. (2008) The Journal of cell biology 182, 727-39. PMID: 18710924
2. Lampert, F. et al. (2018) eLife 7. PMID: 29911972
3. Denti, S. et al. (2004) The Journal of biological chemistry 279, 13027-34. PMID: 14722085
4. Wang, D. et al. (2002) The Journal of biological chemistry 277, 36216-22. PMID: 12147692
5. Rao, MA. et al. (2002) The Journal of biological chemistry 277, 48020-7. PMID: 12361945
6. Harada, N. et al. (2008) Biochemical and biophysical research communications 368, 121-5. PMID: 18222118
7. Kramer, S. et al. (2005) Oncogene 24, 938-44. PMID: 15558019
NoteFor research use only.
图片
参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项，自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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