Anti-Human DEPTOR Polyclonal Antibody (HP016014)

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50ug
100ug

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参考文献
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HP016014

abinScience

种属反应性

Human, Mouse

ELISA, IHC, WB

Rabbit

Polyclonal

E. coli - derived recombinant Human DEPTOR (Ser316-Cys409).

DEPDC6, DEP domain-containing protein 6, DEP domain-containing mTOR-interacting protein, DEPTOR

Purified by antigen affinity column.

Accession号

Q8TB45

Liquid

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

DEP domain-containing mTOR-interacting protein (DEPTOR) is a ~46 kDa protein. Negative regulator of the mTORC1 and mTORC2 complexes: inhibits the protein kinase activity of MTOR, thereby inactivating both complexes. DEPTOR inhibits mTORC1 and mTORC2 to induce autophagy. In contrast to AKT1S1/PRAS40, only partially inhibits mTORC1 activity.

1. Peterson, TR. et al. (2009) Cell 137, 873-86. PMID: 19446321

2. Gao, D. et al. (2011) Molecular cell 44, 290-303. PMID: 22017875

3. Zhao, Y. et al. (2011) Molecular cell 44, 304-16. PMID: 22017876

4. Duan, S. et al. (2011) Molecular cell 44, 317-24. PMID: 22017877

5. Yoon, MS. et al. (2015) Molecular cell 58, 549-56. PMID: 25936805

6. Zhao, L. et al. (2018) The Journal of biological chemistry 293, 4883-4892. PMID: 29382726

7. Wälchli, M. et al. (2021) eLife 10. PMID: 34519268

8. Heimhalt, M. et al. (2021) eLife 10. PMID: 34519269

For research use only.

产品说明书

Anti-Human DEPTOR Polyclonal Antibody.pdf

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

分子量 *

g/mol

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

C₁ (起始浓度)

V₁ (起始体积)

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human DEPTOR Polyclonal Antibody (HP016014)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human DEPTOR Polyclonal Antibody (HP016014)

概述

图片

参考文献

产品说明书

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