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Anti-Human DEPTOR Polyclonal Antibody (ARO-A11164)

概述
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参考文献

概述

货号	ARO-A11164
品牌	ProteoGenix
描述	Anti-Human DEPTOR Polyclonal Antibody (ARO-A11164) is a rabbit polyclonal antibody detecting DEPDC6, DEP domain-containing protein 6, DEP domain-containing mTOR-interacting protein, DEPTOR in ELISA, IHC, WB. Suitable for Human. Highlights Affinity Purified — Minimal background and high purity for reliable results. Multi-Application — Validated across multiple applications.
种属反应性	Human
应用	ELISA, IHC, WB
宿主	Rabbit
克隆类型	Polyclonal
同种型	IgG
免疫原	E. coli - derived recombinant Human DEPTOR (Ser316-Cys409).
靶标	DEPDC6, DEP domain-containing protein 6, DEP domain-containing mTOR-interacting protein, DEPTOR
纯化方式	Purified by antigen affinity column.
Accession号	Q8TB45
状态	Liquid
保存溶液	0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景	DEP domain-containing mTOR-interacting protein (DEPTOR) is a ~46 kDa protein. Negative regulator of the mTORC1 and mTORC2 complexes: inhibits the protein kinase activity of MTOR, thereby inactivating both complexes. DEPTOR inhibits mTORC1 and mTORC2 to induce autophagy. In contrast to AKT1S1/PRAS40, only partially inhibits mTORC1 activity. 1. Peterson, TR. et al. (2009) Cell 137, 873-86. PMID: 19446321 2. Gao, D. et al. (2011) Molecular cell 44, 290-303. PMID: 22017875 3. Zhao, Y. et al. (2011) Molecular cell 44, 304-16. PMID: 22017876 4. Duan, S. et al. (2011) Molecular cell 44, 317-24. PMID: 22017877 5. Yoon, MS. et al. (2015) Molecular cell 58, 549-56. PMID: 25936805 6. Zhao, L. et al. (2018) The Journal of biological chemistry 293, 4883-4892. PMID: 29382726 7. Wälchli, M. et al. (2021) eLife 10. PMID: 34519268 8. Heimhalt, M. et al. (2021) eLife 10. PMID: 34519269
Note	For research use only.

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公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

=

浓度

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体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

×

V₁ (起始体积)

=

工作液

C₂ (终浓度)

×

V₂ (终体积)

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Anti-Human DEPTOR Polyclonal Antibody

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