

| 货号 | MA332014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 品牌 | abinScience | ||||||||
| 种属反应性 | Mouse | ||||||||
| 应用 | ELISA, IHC, WB | ||||||||
| 宿主 | Rabbit | ||||||||
| 克隆类型 | Polyclonal | ||||||||
| 同种型 | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Mouse DAND5 (Ser55-Leu185). | ||||||||
| 靶标 | DAN domain family member 5 (Cerberus-like protein 2) (Cerl-2) | ||||||||
| 纯化方式 | Purified by antigen affinity column. | ||||||||
| Accession号 | Q76LW6 | ||||||||
| 状态 | Liquid | ||||||||
| 保存溶液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| 产品使用信息 |
| ||||||||
| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | DAN domain family member 5 (DAND5) is a ~19 kDa protein. Antagonist of the extracellular signaling protein NODAL, which is required for correct left-right patterning during embryonic development. Antagonist of BMP4 signaling. Antagonist of TGF-beta signaling. Independently of its role in left-right axis establishment, plays a role during heart development, possibly through the regulation of TGF-beta/Nodal signaling pathway. Displays anti-angiogenic activity by inhibiting endothelial sprouting, migration, and proliferation. 1. Marques, S. et al. (2004) Genes & development 18, 2342-7. PMID: 15466485 2. Araújo, AC. et al. (2014) PloS one 9, e102716. PMID: 25033293 3. Popovic, N. et al. (2021) EMBO molecular medicine 13, e12005. PMID: 33587337 | ||||||||
| Note | For research use only. |

Lane 1: MCF-7 cell lysate



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