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Anti-Mouse DAND5 Polyclonal Antibody (ARO-A11011)

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概述
货号ARO-A11011
品牌ProteoGenix
描述
Anti-Mouse DAND5 Polyclonal Antibody (ARO-A11011) is a rabbit polyclonal antibody detecting DAN domain family member 5 (Cerberus-like protein 2) (Cerl-2) in ELISA, IHC, WB. Suitable for Mouse.
Highlights
  • Affinity Purified — Minimal background and high purity for reliable results.
  • Multi-Application — Validated across multiple applications.
种属反应性Mouse
应用ELISA, IHC, WB
宿主Rabbit
克隆类型Polyclonal
同种型IgG
免疫原E. coli - derived recombinant Mouse DAND5 (Ser55-Leu185).
靶标DAN domain family member 5 (Cerberus-like protein 2) (Cerl-2)
纯化方式Purified by antigen affinity column.
Accession号Q76LW6
状态Liquid
保存溶液 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景

DAN domain family member 5 (DAND5) is a ~19 kDa protein. Antagonist of the extracellular signaling protein NODAL, which is required for correct left-right patterning during embryonic development. Antagonist of BMP4 signaling. Antagonist of TGF-beta signaling. Independently of its role in left-right axis establishment, plays a role during heart development, possibly through the regulation of TGF-beta/Nodal signaling pathway. Displays anti-angiogenic activity by inhibiting endothelial sprouting, migration, and proliferation.

1. Marques, S. et al. (2004) Genes & development 18, 2342-7. PMID: 15466485
2. Araújo, AC. et al. (2014) PloS one 9, e102716. PMID: 25033293
3. Popovic, N. et al. (2021) EMBO molecular medicine 13, e12005. PMID: 33587337
NoteFor research use only.
图片
参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项，自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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