

| 货号 | HF679014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 品牌 | abinScience | ||||||||
| 种属反应性 | Human, Mouse, Rat | ||||||||
| 应用 | ELISA, IHC, WB | ||||||||
| 宿主 | Rabbit | ||||||||
| 克隆类型 | Polyclonal | ||||||||
| 同种型 | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Human SORBS2 (Lys865-Thr1001). | ||||||||
| 靶标 | Sorbin and SH3 domain-containing protein 2, ArgBP2, Arg/Abl-interacting protein 2, Sorbin, KIAA0777, ARGBP2, SORBS2, Arg-binding protein 2 | ||||||||
| 纯化方式 | Purified by antigen affinity column. | ||||||||
| Accession号 | O94875 | ||||||||
| 状态 | Liquid | ||||||||
| 保存溶液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| 产品使用信息 |
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| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Sorbin and SH3 domain-containing protein 2 (SORBS2) is a ~124 kDa protein. Adapter protein that plays a role in the assembling of signaling complexes, being a link between ABL kinases and actin cytoskeleton. Can form complex with ABL1 and CBL, thus promoting ubiquitination and degradation of ABL1. May play a role in the regulation of pancreatic cell adhesion, possibly by acting on WASF1 phosphorylation, enhancing phosphorylation by ABL1, as well as dephosphorylation by PTPN12. Isoform 6 increases water and sodium absorption in the intestine and gall-bladder. 1. Taieb, D. et al. (2008) Cancer research 68, 4588-96. PMID: 18559503 | ||||||||
| Note | For research use only. |

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