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Anti-Human SORBS2 Polyclonal Antibody (ARO-A13432)

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概述
货号ARO-A13432
品牌ProteoGenix
描述
Anti-Human SORBS2 Polyclonal Antibody (ARO-A13432) is a rabbit polyclonal antibody detecting Sorbin and SH3 domain-containing protein 2, ArgBP2, Arg/Abl-interacting protein 2, Sorbin, KIAA0777, ARGBP2, SORBS2, Arg-binding protein 2 in ELISA, IHC, WB. Suitable for Human.
Highlights
  • Affinity Purified — Minimal background and high purity for reliable results.
  • Multi-Application — Validated across multiple applications.
种属反应性Human
应用ELISA, IHC, WB
宿主Rabbit
克隆类型Polyclonal
同种型IgG
免疫原E. coli - derived recombinant Human SORBS2 (Lys865-Thr1001).
靶标Sorbin and SH3 domain-containing protein 2, ArgBP2, Arg/Abl-interacting protein 2, Sorbin, KIAA0777, ARGBP2, SORBS2, Arg-binding protein 2
纯化方式Purified by antigen affinity column.
Accession号O94875
状态Liquid
保存溶液 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景

Sorbin and SH3 domain-containing protein 2 (SORBS2) is a ~124 kDa protein. Adapter protein that plays a role in the assembling of signaling complexes, being a link between ABL kinases and actin cytoskeleton. Can form complex with ABL1 and CBL, thus promoting ubiquitination and degradation of ABL1. May play a role in the regulation of pancreatic cell adhesion, possibly by acting on WASF1 phosphorylation, enhancing phosphorylation by ABL1, as well as dephosphorylation by PTPN12. Isoform 6 increases water and sodium absorption in the intestine and gall-bladder.

1. Taieb, D. et al. (2008) Cancer research 68, 4588-96. PMID: 18559503
NoteFor research use only.
图片
参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项，自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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