Anti-Human GNPDA1 Polyclonal Antibody (HW339014)

价格:

规格：

50ug
100ug

数量：

联系我们

一键复制产品信息

概述
图片
参考文献
产品说明书

概述

货号

HW339014

品牌

abinScience

描述

Anti-Human GNPDA1 Polyclonal Antibody (HW339014) is a rabbit polyclonal antibody detecting GNPDA1 in ELISA, IHC, WB. Suitable for Human.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

种属反应性

Human, Mouse

应用

ELISA, IHC, WB

宿主

Rabbit

克隆类型

Polyclonal

同种型

IgG

免疫原

E. coli - derived recombinant Human GNPDA1 (Met1-Asp289).

靶标

GNPDA1, GlcN6P deaminase 1, Glucosamine-6-phosphate deaminase 1, GNPI, GNPDA 1, Oscillin, KIAA0060, HLN, Glucosamine-6-phosphate isomerase 1

纯化方式

Purified by antigen affinity column.

Accession号

P46926

状态

Liquid

保存溶液

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

背景

Glucosamine-6-phosphate deaminase 1 (GNPDA1) is a ~32 kDa protein. Catalyzes the reversible conversion of alpha-D-glucosamine 6-phosphate (GlcN-6P) into beta-D-fructose 6-phosphate (Fru-6P) and ammonium ion, a regulatory reaction step in de novo uridine diphosphate-N-acetyl-alpha-D-glucosamine (UDP-GlcNAc) biosynthesis via hexosamine pathway. Deamination is coupled to aldo-keto isomerization mediating the metabolic flux from UDP-GlcNAc toward Fru-6P. At high ammonium level can drive amination and isomerization of Fru-6P toward hexosamines and UDP-GlcNAc synthesis. Has a role in fine tuning the metabolic fluctuations of cytosolic UDP-GlcNAc and their effects on hyaluronan synthesis that occur during tissue remodeling. Seems to trigger calcium oscillations in mammalian eggs.

1. Alvarez-Añorve, LI. et al. (2011) Biochimica et biophysica acta 1814, 1846-53. PMID: 21807125

2. Oikari, S. et al. (2016) Glycobiology 26, 710-22. PMID: 26887390

Note

For research use only.

图片

Western blot

Western blot analysis was performed using anti-GNPDA1 polyclonal antibody at 1ug/mL on various samples.
Lane 1: U87 cell lysate

参考文献

产品说明书

Anti-Human GNPDA1 Polyclonal Antibody.pdf

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

浓度

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human GNPDA1 Polyclonal Antibody (HW339014)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human GNPDA1 Polyclonal Antibody (HW339014)

概述

图片

参考文献

产品说明书

相关产品推荐

获取报价