Anti-Human RUBCN Polyclonal Antibody (HA317014)

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100ug

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概述
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参考文献
产品说明书

概述

货号

HA317014

品牌

abinScience

描述

Anti-Human RUBCN Polyclonal Antibody (HA317014) is a rabbit polyclonal antibody detecting RUBCN in ELISA, IHC, WB. Suitable for Human.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

种属反应性

Human, Mouse

应用

ELISA, IHC, WB

宿主

Rabbit

克隆类型

Polyclonal

同种型

IgG

免疫原

E. coli - derived recombinant Human RUBCN (Arg710-Thr972).

靶标

RUBCN, KIAA0226, Beclin-1 associated RUN domain containing protein, Rubicon, Baron, Run domain Beclin-1-interacting and cysteine-rich domain-containing protein

纯化方式

Purified by antigen affinity column.

Accession号

Q92622

状态

Liquid

保存溶液

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

背景

Run domain Beclin-1-interacting and cysteine-rich domain-containing protein (RUBCN) is a ~108 kDa protein. Inhibits PIK3C3 activity; under basal conditions negatively regulates PI3K complex II (PI3KC3-C2) function in autophagy. Negatively regulates endosome maturation and degradative endocytic trafficking and impairs autophagosome maturation process. Can sequester UVRAG from association with a class C Vps complex (possibly the HOPS complex) and negatively regulates Rab7 activation.

1. Sun, Q. et al. (2010) Proceedings of the National Academy of Sciences of the United States of America 107, 19338-43. PMID: 20974968

2. Sun, Q. et al. (2011) The Journal of biological chemistry 286, 185-91. PMID: 21062745

Note

For research use only.

图片

参考文献

产品说明书

Anti-Human RUBCN Polyclonal Antibody.pdf

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

浓度

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human RUBCN Polyclonal Antibody (HA317014)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human RUBCN Polyclonal Antibody (HA317014)

概述

图片

参考文献

产品说明书

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