Anti-SLC17A5 Polyclonal Antibody (HV722014)

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100ug

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概述
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参考文献
产品说明书

概述

货号

HV722014

品牌

abinScience

描述

Anti-SLC17A5 Polyclonal Antibody (HV722014) is a rabbit polyclonal antibody detecting SLC17A5 in ELISA, IHC, WB. Suitable for Human, Mouse, and Rat.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

种属反应性

Human

应用

ELISA, IHC, WB

宿主

Rabbit

克隆类型

Polyclonal

同种型

IgG

免疫原

E. coli - derived recombinant Human SLC17A5 (Val65-Gln108).

靶标

H(+)/sialic acid cotransporter, H(+)/nitrate cotransporter, Sialin, AST, Vesicular H(+)/Aspartate-glutamate cotransporter, SLC17A5, Membrane glycoprotein HP59, Solute carrier family 17 member 5

纯化方式

Purified by antigen affinity column.

Accession号

Q9NRA2

状态

Liquid

保存溶液

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

背景

Sialin (SLC17A5) is a ~54 kDa protein. Multifunctional anion transporter that operates via two distinct transport mechanisms, namely proton-coupled anion cotransport and membrane potential-dependent anion transport. Electroneutral proton-coupled acidic monosaccharide symporter, with a sugar to proton stoichiometry of 1:1. Exports glucuronic acid and free sialic acid derived from sialoglycoconjugate degradation out of lysosomes, driven by outwardly directed lysosomal pH gradient. May regulate lysosome function and metabolism of sialylated conjugates that impact oligodendrocyte lineage differentiation and myelinogenesis in the central nervous system. Electrogenic proton-coupled nitrate symporter that transports nitrate ions across the basolateral membrane of salivary gland acinar cells, with nitrate to proton stoichiometry of 2:1.

1. Morin, P. et al. (2004) The EMBO journal 23, 4560-70. PMID: 15510212

2. Miyaji, T. et al. (2011) Journal of neurochemistry 119, 1-5. PMID: 21781115

3. Qin, L. et al. (2012) Proceedings of the National Academy of Sciences of the United States of America 109, 13434-9. PMID: 22778404

4. Lodder-Gadaczek, J. et al. (2013) The Biochemical journal 454, 31-8. PMID: 23889254

Note

For research use only.

图片

参考文献

产品说明书

Anti-SLC17A5 Polyclonal Antibody.pdf

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

浓度

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-SLC17A5 Polyclonal Antibody (HV722014)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-SLC17A5 Polyclonal Antibody (HV722014)

概述

图片

参考文献

产品说明书

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