Anti-Human LYAR Polyclonal Antibody (HV132014)

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100ug

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概述
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参考文献
产品说明书

概述

货号

HV132014

品牌

abinScience

描述

Anti-Human LYAR Polyclonal Antibody (HV132014) is a rabbit polyclonal antibody detecting LYAR in ELISA, IHC, WB. Suitable for Human.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

种属反应性

Human

应用

ELISA, IHC, WB

宿主

Rabbit

克隆类型

Polyclonal

同种型

IgG

免疫原

E. coli - derived recombinant Human LYAR (Gly307-Lys379).

靶标

Cell growth-regulating nucleolar protein, LYAR

纯化方式

Purified by antigen affinity column.

Accession号

Q9NX58

状态

Liquid

保存溶液

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

背景

Cell growth-regulating nucleolar protein (LYAR) is a ~43 kDa protein. Plays a role in the maintenance of the appropriate processing of 47S/45S pre-rRNA to 32S/30S pre-rRNAs and their subsequent processing to produce 18S and 28S rRNAs. Also acts at the level of transcription regulation. Along with PRMT5, binds the gamma-globin (HBG1/HBG2) promoter and represses its expression. In neuroblastoma cells, may also repress the expression of oxidative stress genes, including CHAC1, HMOX1, SLC7A11, ULBP1 and SNORD41 that encodes a small nucleolar RNA. Preferentially binds to a DNA motif containing 5'-GGTTAT-3'.

1. Miyazawa, N. et al. (2014) Genes to cells : devoted to molecular & cellular mechanisms 19, 273-86. PMID: 24495227

2. Ju, J. et al. (2014) Nucleic acids research 42, 9740-52. PMID: 25092918

3. Sun, Y. et al. (2017) Cell death and differentiation 24, 1645-1654. PMID: 28686580

4. Yang, C. et al. (2019) Journal of virology 93. PMID: 31413131

Note

For research use only.

图片

参考文献

产品说明书

Anti-Human LYAR Polyclonal Antibody.pdf

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

浓度

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human LYAR Polyclonal Antibody (HV132014)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human LYAR Polyclonal Antibody (HV132014)

概述

图片

参考文献

产品说明书

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