Anti-Mouse DSG2 Polyclonal Antibody (MC461014)

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50ug
100ug

数量：

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概述
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参考文献
产品说明书

概述

货号

MC461014

品牌

abinScience

描述

Anti-Mouse DSG2 Polyclonal Antibody (MC461014) is a rabbit polyclonal antibody detecting DSG2 in ELISA, IHC, WB. Suitable for Mouse.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

种属反应性

Mouse

应用

ELISA, IHC, WB

宿主

Rabbit

克隆类型

Polyclonal

同种型

IgG

免疫原

E. coli - derived recombinant Mouse DSG2 (Val61-Asn386).

靶标

CDHF5, HDGC, Desmoglein-2, DSG2, Cadherin family member 5

纯化方式

Purified by antigen affinity column.

Accession号

O55111

状态

Liquid

保存溶液

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

背景

Desmoglein-2 (DSG2) is a ~122 kDa protein. A component of desmosome cell-cell junctions which are required for positive regulation of cellular adhesion. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. Required for proliferation and viability of embryonic stem cells in the blastocyst, thereby crucial for progression of post-implantation embryonic development. Maintains pluripotency by regulating epithelial to mesenchymal transition/mesenchymal to epithelial transition (EMT/MET) via interacting with and sequestering CTNNB1 to sites of cell-cell contact, thereby reducing translocation of CTNNB1 to the nucleus and subsequent transcription of CTNNB1/TCF-target genes. Promotes pluripotency and the multi-lineage differentiation potential of hematopoietic stem cells.

1. Eshkind, L. et al. (2002) European journal of cell biology 81, 592-8. PMID: 12494996

2. Park, J. et al. (2018) Stem cell reports 11, 115-127. PMID: 29910125

3. Ebert, LM. et al. (2016) Angiogenesis 19, 463-86. PMID: 27338829

4. Kant, S. et al. (2015) Circulation. Cardiovascular genetics 8, 553-63. PMID: 26085008

5. Myo Min, KK. et al. (2022) Cell death & disease 13, 911. PMID: 36309486

6. Xu, T. et al. (2024) Kidney international 105, 1035-1048. PMID: 38395410

Note

For research use only.

图片

参考文献

产品说明书

Anti-Mouse DSG2 Polyclonal Antibody.pdf

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

浓度

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Mouse DSG2 Polyclonal Antibody (MC461014)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Mouse DSG2 Polyclonal Antibody (MC461014)

概述

图片

参考文献

产品说明书

相关产品推荐

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