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Anti-Mouse DSG2 Polyclonal Antibody (ARO-A12892)

概述
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概述

货号	ARO-A12892
品牌	ProteoGenix
描述	Anti-Mouse DSG2 Polyclonal Antibody (ARO-A12892) is a rabbit polyclonal antibody detecting CDHF5, HDGC, Desmoglein-2, DSG2, Cadherin family member 5 in ELISA, IHC, WB. Suitable for Mouse. Highlights Affinity Purified — Minimal background and high purity for reliable results. Multi-Application — Validated across multiple applications.
种属反应性	Mouse
应用	ELISA, IHC, WB
宿主	Rabbit
克隆类型	Polyclonal
同种型	IgG
免疫原	E. coli - derived recombinant Mouse DSG2 (Val61-Asn386).
靶标	CDHF5, HDGC, Desmoglein-2, DSG2, Cadherin family member 5
纯化方式	Purified by antigen affinity column.
Accession号	O55111
状态	Liquid
保存溶液	0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景	Desmoglein-2 (DSG2) is a ~122 kDa protein. A component of desmosome cell-cell junctions which are required for positive regulation of cellular adhesion. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. Required for proliferation and viability of embryonic stem cells in the blastocyst, thereby crucial for progression of post-implantation embryonic development. Maintains pluripotency by regulating epithelial to mesenchymal transition/mesenchymal to epithelial transition (EMT/MET) via interacting with and sequestering CTNNB1 to sites of cell-cell contact, thereby reducing translocation of CTNNB1 to the nucleus and subsequent transcription of CTNNB1/TCF-target genes. Promotes pluripotency and the multi-lineage differentiation potential of hematopoietic stem cells. 1. Eshkind, L. et al. (2002) European journal of cell biology 81, 592-8. PMID: 12494996 2. Park, J. et al. (2018) Stem cell reports 11, 115-127. PMID: 29910125 3. Ebert, LM. et al. (2016) Angiogenesis 19, 463-86. PMID: 27338829 4. Kant, S. et al. (2015) Circulation. Cardiovascular genetics 8, 553-63. PMID: 26085008 5. Myo Min, KK. et al. (2022) Cell death & disease 13, 911. PMID: 36309486 6. Xu, T. et al. (2024) Kidney international 105, 1035-1048. PMID: 38395410
Note	For research use only.

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参考文献

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

=

浓度

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体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

×

V₁ (起始体积)

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工作液

C₂ (终浓度)

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V₂ (终体积)

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Anti-Mouse DSG2 Polyclonal Antibody

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