Anti-Mouse CD19 Polyclonal Antibody (MB996014)

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概述
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参考文献
产品说明书

概述

货号

MB996014

品牌

abinScience

描述

Anti-Mouse CD19 Polyclonal Antibody (MB996014) is a rabbit polyclonal antibody detecting CD19 in ELISA, IHC, WB. Suitable for Mouse.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

种属反应性

Mouse

应用

ELISA, IHC, WB

宿主

Rabbit

克隆类型

Polyclonal

同种型

IgG

免疫原

E. coli - derived recombinant Mouse CD19 (Ser23-Ser276).

靶标

B-lymphocyte antigen CD19, B-lymphocyte surface antigen B4, CD19, Differentiation antigen CD19, T-cell surface antigen Leu-12

内毒素水平

Please contact with the lab for this information.

纯度

>90% as determined by SDS-PAGE.

纯化方式

Purified by antigen affinity column.

Accession号

P25918

状态

Liquid

保存溶液

0.01M PBS, pH 7.4, 50% glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

背景

B-lymphocyte antigen CD19 is a ~60 kDa protein. Functions as a coreceptor for the B-cell antigen receptor complex (BCR) on B-lymphocytes. Decreases the threshold for activation of downstream signaling pathways and for triggering B-cell responses to antigens. Activates signaling pathways that lead to the activation of phosphatidylinositol 3-kinase and the mobilization of intracellular Ca(2+) stores. Is not required for early steps during B cell differentiation in the blood marrow. Required for normal differentiation of B-1 cells. CD19 is the therapeutic target of tafasitamab (Monjuvi).

1. Wang, Y. et al. (2002) Immunity 17, 501-14. PMID: 12387743

2. Ishiura, N. et al. (2010) European journal of immunology 40, 1192-204. PMID: 20101619

3. Buhl, AM. et al. (1997) The Journal of experimental medicine 186, 1897-910. PMID: 9382888

4. Engel, P. et al. (1995) Immunity 3, 39-50. PMID: 7542548

5. Rickert, RC. et al. (1995) Nature 376, 352-5. PMID: 7543183

6. Sato, S. et al. (1997) Journal of immunology (Baltimore, Md. : 1950) 159, 3278-87. PMID: 9317126

Note

For research use only.

图片

参考文献

产品说明书

Anti-Mouse CD19 Polyclonal Antibody.pdf

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

浓度

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Mouse CD19 Polyclonal Antibody (MB996014)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Mouse CD19 Polyclonal Antibody (MB996014)

概述

图片

参考文献

产品说明书

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