Anti-Mouse ROBO3 Polyclonal Antibody (MA318014)

价格:

规格：

50ug
100ug

数量：

联系我们

一键复制产品信息

概述
图片
参考文献
产品说明书

概述

货号

MA318014

品牌

abinScience

描述

Anti-Mouse ROBO3 Polyclonal Antibody (MA318014) is a rabbit polyclonal antibody detecting ROBO3 in ELISA, IHC, WB. Suitable for Mouse.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

种属反应性

Mouse

应用

ELISA, IHC, WB

宿主

Rabbit

克隆类型

Polyclonal

同种型

IgG

免疫原

E. coli - derived recombinant Mouse ROBO3 (Gly173-Val345).

靶标

Roundabout-like protein 3, ROBO3, Roundabout homolog 3

纯化方式

Purified by antigen affinity column.

Accession号

Q9Z2I4

状态

Liquid

保存溶液

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

背景

Roundabout homolog 3 (ROBO3) is a ~149 kDa protein. Receptor involved in axon guidance during development. Acts as a multifunctional regulator of pathfinding that simultaneously mediates NELL2 repulsion, inhibits SLIT repulsion, and facilitates Netrin-1/NTN1 attraction. In spinal cord development plays a role in guiding commissural axons probably by preventing premature sensitivity to Slit proteins thus inhibiting Slit signaling through ROBO1/ROBO2. Binding OF NELL2 to the receptor ROBO3 promotes oligomerization of ROBO3, resulting in the repulsion of commissural axons in the midline. ROBO3 also indirectly boosts axon attraction to NTN1 without interacting with NTN1 itself.

1. Sabatier, C. et al. (2004) Cell 117, 157-69. PMID: 15084255

2. Chen, Z. et al. (2008) Neuron 58, 325-32. PMID: 18466743

3. Zelina, P. et al. (2014) Neuron 84, 1258-72. PMID: 25433640

4. Zhuang, M. et al. (2019) Nucleic acids research 47, 4765-4777. PMID: 30843071

5. Pak, JS. et al. (2020) Nature communications 11, 1489. PMID: 32198364

Note

For research use only.

图片

参考文献

产品说明书

Anti-Mouse ROBO3 Polyclonal Antibody.pdf

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

浓度

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Mouse ROBO3 Polyclonal Antibody (MA318014)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Mouse ROBO3 Polyclonal Antibody (MA318014)

概述

图片

参考文献

产品说明书

相关产品推荐

获取报价