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Anti-Human CTTN Polyclonal Antibody (HC329014)

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概述
货号HC329014
品牌abinScience
描述
Anti-Human CTTN Polyclonal Antibody (HC329014) is a rabbit polyclonal antibody detecting CTTN in ELISA, IHC, WB. Suitable for Human.
Highlights
  • Affinity Purified — Minimal background and high purity for reliable results.
  • Multi-Application — Validated across multiple applications.
种属反应性Human, Mouse
应用ELISA, IHC, WB
宿主Rabbit
同种型IgG
克隆类型Polyclonal
免疫原E. coli - derived recombinant Human CTTN (Met1-Asn491).
靶标Src substrate cortactin, Oncogene EMS1, CTTN, Amplaxin, EMS1
纯化方式Purified by antigen affinity column.
Accession号Q14247
状态Liquid
保存溶液 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息
应用方法 稀释比例
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景

Src substrate cortactin (CTTN) is a ~61 kDa protein. Contributes to the organization of the actin cytoskeleton and cell shape. Plays a role in the formation of lamellipodia and in cell migration. Plays a role in the regulation of neuron morphology, axon growth and formation of neuronal growth cones. Through its interaction with CTTNBP2, involved in the regulation of neuronal spine density. Plays a role in focal adhesion assembly and turnover.

1. von Holleben, M. et al. (2011) The Journal of biological chemistry 286, 13489-501. PMID: 21296879
2. Dudek, SM. et al. (2010) Molecular biology of the cell 21, 4042-56. PMID: 20861316
3. Williams, MR. et al. (2007) Proceedings of the National Academy of Sciences of the United States of America 104, 17412-7. PMID: 17959782
4. Herrmann, S. et al. (2012) The Journal of biological chemistry 287, 44151-63. PMID: 23144454
5. Hashimoto, S. et al. (2006) Proceedings of the National Academy of Sciences of the United States of America 103, 7036-41. PMID: 16636290
NoteFor research use only.
图片
参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量,自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项,自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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