

| 货号 | ARO-A12758 |
|---|---|
| 品牌 | ProteoGenix |
| 描述 |
Anti-Human CTTN Polyclonal Antibody (ARO-A12758) is a rabbit polyclonal antibody detecting Src substrate cortactin, Oncogene EMS1, CTTN, Amplaxin, EMS1 in ELISA, IHC, WB. Suitable for Human.
Highlights
|
| 种属反应性 | Human |
| 应用 | ELISA, IHC, WB |
| 宿主 | Rabbit |
| 同种型 | IgG |
| 克隆类型 | Polyclonal |
| 免疫原 | E. coli - derived recombinant Human CTTN (Met1-Asn491). |
| 靶标 | Src substrate cortactin, Oncogene EMS1, CTTN, Amplaxin, EMS1 |
| 纯化方式 | Purified by antigen affinity column. |
| Accession号 | Q14247 |
| 状态 | Liquid |
| 保存溶液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 背景 | Src substrate cortactin (CTTN) is a ~61 kDa protein. Contributes to the organization of the actin cytoskeleton and cell shape. Plays a role in the formation of lamellipodia and in cell migration. Plays a role in the regulation of neuron morphology, axon growth and formation of neuronal growth cones. Through its interaction with CTTNBP2, involved in the regulation of neuronal spine density. Plays a role in focal adhesion assembly and turnover. 1. von Holleben, M. et al. (2011) The Journal of biological chemistry 286, 13489-501. PMID: 21296879 2. Dudek, SM. et al. (2010) Molecular biology of the cell 21, 4042-56. PMID: 20861316 3. Williams, MR. et al. (2007) Proceedings of the National Academy of Sciences of the United States of America 104, 17412-7. PMID: 17959782 4. Herrmann, S. et al. (2012) The Journal of biological chemistry 287, 44151-63. PMID: 23144454 5. Hashimoto, S. et al. (2006) Proceedings of the National Academy of Sciences of the United States of America 103, 7036-41. PMID: 16636290 |
| Note | For research use only. |

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