

| 货号 | HT318014 | ||||||||
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| 品牌 | abinScience | ||||||||
| 描述 |
Anti-MDM4 Polyclonal Antibody (HT318014) is a rabbit polyclonal antibody detecting MDM4 in ELISA, IHC, WB. Suitable for Human.
Highlights
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| 种属反应性 | Human | ||||||||
| 应用 | ELISA, IHC, WB | ||||||||
| 宿主 | Rabbit | ||||||||
| 同种型 | IgG | ||||||||
| 克隆类型 | Polyclonal | ||||||||
| 免疫原 | E. coli - derived recombinant Human MDM4 (Thr2-Asp134). | ||||||||
| 靶标 | MDM4, Mdm2-like p53-binding protein, MDMX, p53-binding protein Mdm4, Protein Mdm4, Protein Mdmx, Double minute 4 protein | ||||||||
| 纯化方式 | Purified by antigen affinity column. | ||||||||
| Accession号 | O15151 | ||||||||
| 状态 | Liquid | ||||||||
| 保存溶液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| 产品使用信息 |
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| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Protein Mdm4 is a ~54 kDa protein. Contributes to p53/TP53 regulation. Inhibits p53/TP53- and p73/TP73-mediated cell cycle arrest and apoptosis by binding their transcriptional activation domains. Inhibits degradation of MDM2. Can reverse MDM2-targeted degradation of TP53 while maintaining suppression of TP53 transactivation and apoptotic functions. 1. Toufektchan, E. et al. (2020) Science advances 6, eaay3511. PMID: 32300648 | ||||||||
| Note | For research use only. |

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