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Anti-Human MDM4 Recombinant Nanobody (SAA1189) (HT318013)

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规格:
  • 50ug
  • 100ug
  • 1mg
数量:
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概述
货号HT318013
品牌abinScience
描述
Anti-Human MDM4 Nanobody (SAA1189) [SAA1189] (HT318013) is a alpaca monoclonal antibody detecting Protein Mdm4 in ELISA. Suitable for Human.
种属反应性Human
应用ELISA
宿主Alpaca
克隆类型Monoclonal
同种型VHH-8His-Cys-tag
克隆号SAA1189
靶标MDM4, Mdm2-like p53-binding protein, MDMX, p53-binding protein Mdm4, Protein Mdm4, Protein Mdmx, Double minute 4 protein
内毒素水平< 10 EU/mg as determined by LAL method.
纯度>95% as determined by SDS-PAGE.
纯化方式Purified by Nickel column.
Accession号O15151
状态Liquid
保存溶液 0.01M PBS pH 7.4.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息
应用方法 稀释比例
ELISA 1:2000-1:20000
稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景

Protein Mdm4 is a ~54 kDa protein. Contributes to p53/TP53 regulation. Inhibits p53/TP53- and p73/TP73-mediated cell cycle arrest and apoptosis by binding their transcriptional activation domains. Inhibits degradation of MDM2. Can reverse MDM2-targeted degradation of TP53 while maintaining suppression of TP53 transactivation and apoptotic functions.

1. Toufektchan, E. et al. (2020) Science advances 6, eaay3511. PMID: 32300648
NoteFor research use only.
图片
  • SDS-PAGE

    SDS-PAGE for Anti-Human MDM4 Nanobody (SAA1189)

参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量,自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项,自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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