Anti-Human CD85g/LILRA4/ILT7 Polyclonal Antibody (HX894014)

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概述
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参考文献
产品说明书

概述

货号

HX894014

品牌

abinScience

描述

Anti-Human CD85g/LILRA4/ILT7 Polyclonal Antibody (HX894014) is a rabbit polyclonal antibody detecting LILRA4 in ELISA, IHC, WB. Suitable for Human.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

种属反应性

Human

应用

ELISA, IHC, WB

宿主

Rabbit

同种型

IgG

克隆类型

Polyclonal

免疫原

E. coli - derived recombinant Human CD85g/LILRA4/ILT7 (Glu24-Gly419).

靶标

Leukocyte immunoglobulin-like receptor subfamily A member 4, CD85 antigen-like family member G, Immunoglobulin-like transcript 7, ILT-7, CD85g, LILRA4, ILT7

纯化方式

Purified by antigen affinity column.

Accession号

P59901

状态

Liquid

保存溶液

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

背景

Leukocyte immunoglobulin-like receptor subfamily A member 4 (CD85g/LILRA4) is a ~55 kDa protein. Functions coreceptor to limit the innate immune responses to viral infections; signaling occurs via FCER1G. Down-regulates the production of IFNA1, IFNA2, IFNA4, IFNB1 and TNF by plasmacytoid dendritic cells that have been exposed to influenza virus or cytidine-phosphate-guanosine (CpG) dinucleotides, indicating it functions as a negative regulator of TLR7 and TLR9 signaling cascades. Down-regulates interferon production in response to interaction with BST2 on HIV-1 infected cells. Activates a signaling cascade in complex with FCER1G that results in phosphorylation of Src family and Syk kinases and thereby triggers mobilization of intracellular Ca(2+). Does not interfere with the differentiation of plasmacytoid dendritic cells into antigen-presenting cells.

1. Cao, W. et al. (2006) The Journal of experimental medicine 203, 1399-405. PMID: 16735691

2. Cao, W. et al. (2009) The Journal of experimental medicine 206, 1603-14. PMID: 19564354

3. Tavano, B. et al. (2014) PloS one 9, e89414. PMID: 24586760

4. Bego, MG. et al. (2015) PLoS pathogens 11, e1005024. PMID: 26172439

Note

For research use only.

图片

参考文献

产品说明书

Anti-Human CD85g/LILRA4/ILT7 Polyclonal Antibody.pdf

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

浓度

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human CD85g/LILRA4/ILT7 Polyclonal Antibody (HX894014)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human CD85g/LILRA4/ILT7 Polyclonal Antibody (HX894014)

概述

图片

参考文献

产品说明书

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