Anti-Human CD367/CLEC4A Polyclonal Antibody (HV145014)

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100ug

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概述
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参考文献
产品说明书

概述

货号

HV145014

品牌

abinScience

描述

Anti-Human CD367/CLEC4A Polyclonal Antibody (HV145014) is a rabbit polyclonal antibody detecting CLEC4A in ELISA, IHC, WB. Suitable for Human.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

种属反应性

Human

应用

ELISA, IHC, WB

宿主

Rabbit

克隆类型

Polyclonal

同种型

IgG

免疫原

E. coli - derived recombinant Human CD367/CLEC4A (Gln70-Leu237).

靶标

C-type lectin domain family 4 member A, C-type lectin DDB27, C-type lectin superfamily member 6, Dendritic cell immunoreceptor, Lectin-like immunoreceptor, CD367, CLEC4A, CLECSF6, DCIR, LLIR, HDCGC13P

纯化方式

Purified by antigen affinity column.

Accession号

Q9UMR7

状态

Liquid

保存溶液

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

背景

C-type lectin domain family 4 member A (CD367/CLEC4A) is a ~27 kDa protein. C-type lectin receptor that binds carbohydrates mannose and fucose but also weakly interacts with N-acetylglucosamine (GlcNAc) in a Ca(2+)-dependent manner. Involved in regulating immune reactivity. Once triggered by antigen, it is internalized by clathrin-dependent endocytosis and delivers its antigenic cargo into the antigen presentation pathway resulting in cross-priming of CD8(+) T cells. This cross-presentation and cross-priming are enhanced by TLR7 and TLR8 agonists with increased expansion of the CD8(+) T cells, high production of IFNG and TNF with reduced levels of IL4, IL5 and IL13. In plasmacytoid dendritic cells, inhibits TLR9-mediated IFNA and TNF production.

1. Nagae, M. et al. (2016) FEBS letters 590, 1280-8. PMID: 27015765

2. Bates, EE. et al. (1999) Journal of immunology (Baltimore, Md. : 1950) 163, 1973-83. PMID: 10438934

3. Meyer-Wentrup, F. et al. (2008) Blood 111, 4245-53. PMID: 18258799

4. Klechevsky, E. et al. (2010) Blood 116, 1685-97. PMID: 20530286

Note

For research use only.

图片

参考文献

产品说明书

Anti-Human CD367/CLEC4A Polyclonal Antibody.pdf

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

浓度

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human CD367/CLEC4A Polyclonal Antibody (HV145014)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human CD367/CLEC4A Polyclonal Antibody (HV145014)

概述

图片

参考文献

产品说明书

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