Anti-Human FADS1/Delta 5 desaturase Polyclonal Antibody (HT042014)

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概述
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参考文献
产品说明书

概述

货号

HT042014

品牌

abinScience

描述

Anti-Human FADS1/Delta 5 desaturase Polyclonal Antibody (HT042014) is a rabbit polyclonal antibody detecting Delta(5) desaturase in ELISA, IHC, WB. Suitable for Human.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

种属反应性

Human

应用

ELISA, IHC, WB

宿主

Rabbit

克隆类型

Polyclonal

同种型

IgG

免疫原

E. coli - derived recombinant Human FADS1/Delta 5 desaturase (Met1-Arg121).

靶标

Acyl-CoA (8-3)-desaturase, 1.14.19.44, Delta(5) fatty acid desaturase, D5D, Delta(5) desaturase, Delta-5 desaturase, Fatty acid desaturase 1, FADS1, FADSD5

纯化方式

Purified by antigen affinity column.

Accession号

O60427

状态

Liquid

保存溶液

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

背景

Acyl-CoA (8-3)-desaturase (FADS1/Delta 5 desaturase) is a ~51 kDa protein. Acts as a front-end fatty acyl-coenzyme A (CoA) desaturase that introduces a cis double bond at carbon 5 located between a preexisting double bond and the carboxyl end of the fatty acyl chain. Involved in biosynthesis of highly unsaturated fatty acids (HUFA) from the essential polyunsaturated fatty acids (PUFA) linoleic acid (LA) (18:2n-6) and alpha-linolenic acid (ALA) (18:3n-3) precursors. Specifically, desaturates dihomo-gamma-linoleoate (DGLA) (20:3n-6) and eicosatetraenoate (ETA) (20:4n-3) to generate arachidonate (AA) (20:4n-6) and eicosapentaenoate (EPA) (20:5n-3), respectively. As a rate limiting enzyme for DGLA (20:3n-6) and AA (20:4n-6)-derived eicosanoid biosynthesis, controls the metabolism of inflammatory lipids like prostaglandin E2, critical for efficient acute inflammatory response and maintenance of epithelium homeostasis. Contributes to membrane phospholipid biosynthesis by providing AA (20:4n-6) as a major acyl chain esterified into phospholipids.

1. Cho, HP. et al. (1999) The Journal of biological chemistry 274, 37335-9. PMID: 10601301

2. Leonard, AE. et al. (2000) The Biochemical journal 347 Pt 3, 719-24. PMID: 10769175

Note

For research use only.

图片

参考文献

产品说明书

Anti-Human FADS1/Delta 5 desaturase Polyclonal Antibody.pdf

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

浓度

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human FADS1/Delta 5 desaturase Polyclonal Antibody (HT042014)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human FADS1/Delta 5 desaturase Polyclonal Antibody (HT042014)

概述

图片

参考文献

产品说明书

相关产品推荐

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