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Anti-Human FADS1/Delta 5 desaturase Recombinant Antibody (SAA1792) (HT042013)

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规格:
  • 50ug
  • 100ug
  • 1mg
数量:
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概述
货号HT042013
品牌abinScience
种属反应性Human
应用ELISA
宿主Mouse
克隆类型Monoclonal
同种型IgG2a, kappa
克隆号SAA1792
靶标D5D, FADS1, Delta(5) fatty acid desaturase, Acyl-CoA (8-3)-desaturase, Fatty acid desaturase 1, Delta(5) desaturase, Delta-5 desaturase, FADSD5
内毒素水平Please contact with the lab for this information.
纯度>95% as determined by SDS-PAGE.
纯化方式Protein A/G purified from cell culture supernatant.
Accession号O60427
RRIDAnti-Human FADS1/Delta 5 desaturase Antibody (SAA1792) (abinScience Cat# HT042013, RRID:AB_3727554)
状态Liquid
保存溶液 0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息
应用方法 稀释比例
ELISA 1:2000-1:20000
稳定性和存储Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
背景

Acyl-CoA (8-3)-desaturase (FADS1/Delta 5 desaturase) is a ~51 kDa protein. Acts as a front-end fatty acyl-coenzyme A (CoA) desaturase that introduces a cis double bond at carbon 5 located between a preexisting double bond and the carboxyl end of the fatty acyl chain. Involved in biosynthesis of highly unsaturated fatty acids (HUFA) from the essential polyunsaturated fatty acids (PUFA) linoleic acid (LA) (18:2n-6) and alpha-linolenic acid (ALA) (18:3n-3) precursors. Specifically, desaturates dihomo-gamma-linoleoate (DGLA) (20:3n-6) and eicosatetraenoate (ETA) (20:4n-3) to generate arachidonate (AA) (20:4n-6) and eicosapentaenoate (EPA) (20:5n-3), respectively. As a rate limiting enzyme for DGLA (20:3n-6) and AA (20:4n-6)-derived eicosanoid biosynthesis, controls the metabolism of inflammatory lipids like prostaglandin E2, critical for efficient acute inflammatory response and maintenance of epithelium homeostasis. Contributes to membrane phospholipid biosynthesis by providing AA (20:4n-6) as a major acyl chain esterified into phospholipids.

1. Cho, HP. et al. (1999) The Journal of biological chemistry 274, 37335-9. PMID: 10601301
2. Leonard, AE. et al. (2000) The Biochemical journal 347 Pt 3, 719-24. PMID: 10769175
NoteFor research use only.
图片
  • SDS-PAGE

    SDS-PAGE for Anti-Human FADS1/Delta 5 desaturase Antibody (SAA1792)

参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量,自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项,自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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