

| 货号 | HY199014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 品牌 | abinScience | ||||||||
| 描述 |
Anti-Human SLC2A1 Polyclonal Antibody (HY199014) is a rabbit polyclonal antibody detecting SLC2A1 in ELISA, IHC, WB. Suitable for Human.
Highlights
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| 种属反应性 | Human | ||||||||
| 应用 | ELISA, IHC, WB | ||||||||
| 宿主 | Rabbit | ||||||||
| 克隆类型 | Polyclonal | ||||||||
| 同种型 | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Human SLC2A1. | ||||||||
| 靶标 | Solute carrier family 2, facilitated glucose transporter member 1, Glucose transporter type 1, erythrocyte/brain, GLUT-1, HepG2 glucose transporter, SLC2A1, GLUT1 | ||||||||
| 纯化方式 | Purified by antigen affinity column. | ||||||||
| Accession号 | P11166 | ||||||||
| 状态 | Liquid | ||||||||
| 保存溶液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| 产品使用信息 |
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| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Solute carrier family 2, facilitated glucose transporter member 1 (SLC2A1) is a ~54 kDa protein. Facilitative glucose transporter, which is responsible for constitutive or basal glucose uptake. Has a very broad substrate specificity; can transport a wide range of aldoses including both pentoses and hexoses. Most important energy carrier of the brain: present at the blood-brain barrier and assures the energy-independent, facilitative transport of glucose into the brain. In association with BSG and NXNL1, promotes retinal cone survival by increasing glucose uptake into photoreceptors. Required for mesendoderm differentiation. 1. Klepper, J. et al. (1999) Neurochemical research 24, 587-94. PMID: 10227690 2. Woodrow, CJ. et al. (2000) Proceedings of the National Academy of Sciences of the United States of America 97, 9931-6. PMID: 10954735 3. Mueckler, M. et al. (2008) The Journal of biological chemistry 283, 11550-5. PMID: 18245775 4. Mueckler, M. et al. (2009) Biochemistry 48, 5934-42. PMID: 19449892 5. Lee, EE. et al. (2015) Molecular cell 58, 845-53. PMID: 25982116 6. Kapoor, K. et al. (2016) Proceedings of the National Academy of Sciences of the United States of America 113, 4711-6. PMID: 27078104 7. Jiang, X. et al. (2020) Cell 183, 258-268.e12. PMID: 32860739 | ||||||||
| Note | For research use only. |

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