Recombinant Human SLC2A1 Protein, N-His (PX-P5926)
概述
图片
参考文献
概述
货号
PX-P5926
品牌
ProteoGenix
描述
Recombinant Human SLC2A1 Protein, N-His (PX-P5926) expressed in E. coli, Purity: >90% as determined by SDS-PAGE..
Highlights
High Purity (>90% as determined by SDS-PAGE.) — Verified by SDS-PAGE for downstream accuracy.
E. coli Expression — Optimized for functional studies.
表达系统
E. coli
Accession号
P11166
蛋白长度
Met251-Glu329
应用
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
种属
Homo sapiens (Human)
性质
Recombinant
内毒素水平
Please contact with the lab for this information.
纯度
>90% as determined by SDS-PAGE.
预测分子量
11.08 kDa
状态
Lyophilized
保存溶液
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
重悬
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
运输
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
稳定性和存储
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
别名
Solute carrier family 2, facilitated glucose transporter member 1, GLUT-1, Glucose transporter type 1, erythrocyte/brain, HepG2 glucose transporter, GLUT1, SLC2A1
背景
Solute carrier family 2, facilitated glucose transporter member 1 (SLC2A1) is a ~54 kDa protein. Facilitative glucose transporter, which is responsible for constitutive or basal glucose uptake. Has a very broad substrate specificity; can transport a wide range of aldoses including both pentoses and hexoses. Most important energy carrier of the brain: present at the blood-brain barrier and assures the energy-independent, facilitative transport of glucose into the brain. In association with BSG and NXNL1, promotes retinal cone survival by increasing glucose uptake into photoreceptors. Required for mesendoderm differentiation.
1. Klepper, J. et al. (1999) Neurochemical research 24, 587-94. PMID: 10227690
2. Woodrow, CJ. et al. (2000) Proceedings of the National Academy of Sciences of the United States of America 97, 9931-6. PMID: 10954735
3. Mueckler, M. et al. (2008) The Journal of biological chemistry 283, 11550-5. PMID: 18245775
4. Mueckler, M. et al. (2009) Biochemistry 48, 5934-42. PMID: 19449892
