Anti-Human AQP4/Aquaporin-4 Polyclonal Antibody (HX181014)

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100ug

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概述
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参考文献
产品说明书

概述

货号

HX181014

品牌

abinScience

描述

Anti-Human AQP4/Aquaporin-4 Polyclonal Antibody (HX181014) is a rabbit polyclonal antibody detecting Aquaporin-4 in ELISA, IHC, WB. Suitable for Human.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

种属反应性

Human, Mouse, Rat

应用

ELISA, IHC, WB

宿主

Rabbit

克隆类型

Polyclonal

同种型

IgG

免疫原

E. coli - derived recombinant Human AQP4/Aquaporin-4.

靶标

Aquaporin-4, AQP-4, Mercurial-insensitive water channel, MIWC, WCH4, AQP4

纯化方式

Purified by antigen affinity column.

Accession号

P55087

状态

Liquid

保存溶液

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

背景

Aquaporin-4 (AQP4) is a ~34 kDa protein. Forms a water-specific channel. Plays an important role in brain water homeostasis. It is involved in glymphatic solute transport and is required for a normal rate of water exchange across the blood brain interface. Required for normal levels of cerebrospinal fluid influx into the brain cortex and parenchyma along paravascular spaces that surround penetrating arteries, and for normal drainage of interstitial fluid along paravenous drainage pathways. Thereby, it is required for normal clearance of solutes from the brain interstitial fluid, including soluble beta-amyloid peptides derived from APP.

1. Ho, JD. et al. (2009) Proceedings of the National Academy of Sciences of the United States of America 106, 7437-42. PMID: 19383790

2. Yang, B. et al. (1995) The Journal of biological chemistry 270, 22907-13. PMID: 7559426

3. Misaka, T. et al. (1996) FEBS letters 381, 208-12. PMID: 8601457

4. Passchier, EMJ. et al. (2023) Brain : a journal of neurology 146, 3444-3454. PMID: 37143309

Note

For research use only.

图片

参考文献

产品说明书

Anti-Human AQP4/Aquaporin-4 Polyclonal Antibody.pdf

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

浓度

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human AQP4/Aquaporin-4 Polyclonal Antibody (HX181014)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human AQP4/Aquaporin-4 Polyclonal Antibody (HX181014)

概述

图片

参考文献

产品说明书

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