

| 货号 | HX181013 | ||||
|---|---|---|---|---|---|
| 品牌 | abinScience | ||||
| 种属反应性 | Human | ||||
| 应用 | ELISA, FCM, IF | ||||
| 宿主 | Mouse | ||||
| 克隆类型 | Monoclonal | ||||
| 同种型 | IgG2a, kappa | ||||
| 克隆号 | SAA1755 | ||||
| 靶标 | WCH4, Aquaporin-4, Mercurial-insensitive water channel, AQP-4, MIWC, AQP4 | ||||
| 内毒素水平 | Please contact with the lab for this information. | ||||
| 纯度 | >95% as determined by SDS-PAGE. | ||||
| 纯化方式 | Protein A/G purified from cell culture supernatant. | ||||
| Accession号 | P55087 | ||||
| RRID | Anti-Human AQP4/Aquaporin-4 Antibody (SAA1755) (abinScience Cat# HX181013, RRID:AB_3727516) | ||||
| 状态 | Liquid | ||||
| 保存溶液 | 0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| 产品使用信息 |
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| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. | ||||
| 背景 | Aquaporin-4 (AQP4) is a ~34 kDa protein. Forms a water-specific channel. Plays an important role in brain water homeostasis. It is involved in glymphatic solute transport and is required for a normal rate of water exchange across the blood brain interface. Required for normal levels of cerebrospinal fluid influx into the brain cortex and parenchyma along paravascular spaces that surround penetrating arteries, and for normal drainage of interstitial fluid along paravenous drainage pathways. Thereby, it is required for normal clearance of solutes from the brain interstitial fluid, including soluble beta-amyloid peptides derived from APP. 1. Ho, JD. et al. (2009) Proceedings of the National Academy of Sciences of the United States of America 106, 7437-42. PMID: 19383790 2. Yang, B. et al. (1995) The Journal of biological chemistry 270, 22907-13. PMID: 7559426 3. Misaka, T. et al. (1996) FEBS letters 381, 208-12. PMID: 8601457 4. Passchier, EMJ. et al. (2023) Brain : a journal of neurology 146, 3444-3454. PMID: 37143309 | ||||
| Note | For research use only. | ||||
| Isotype Control | Mouse IgG2a (Fc Silence) Recombinant Isotype Control (MOPC 173) (MF533023) |

SDS-PAGE for Anti-Human AQP4/Aquaporin-4 Antibody (SAA1755).



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