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Anti-Human AQP4/Aquaporin-4 Recombinant Antibody (SAA1755) (HX181013)

价格:
规格:
  • 50ug
  • 100ug
  • 1mg
数量:
  • 概述

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  • 参考文献

  • 产品说明书

概述
货号HX181013
品牌abinScience
种属反应性Human
应用ELISA, FCM, IF
宿主Mouse
克隆类型Monoclonal
同种型IgG2a, kappa
克隆号SAA1755
靶标WCH4, Aquaporin-4, Mercurial-insensitive water channel, AQP-4, MIWC, AQP4
内毒素水平Please contact with the lab for this information.
纯度>95% as determined by SDS-PAGE.
纯化方式Protein A/G purified from cell culture supernatant.
Accession号P55087
RRIDAnti-Human AQP4/Aquaporin-4 Antibody (SAA1755) (abinScience Cat# HX181013, RRID:AB_3727516)
状态Liquid
保存溶液 0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息
应用方法 稀释比例
ELISA 1:2000-1:20000
稳定性和存储Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
背景

Aquaporin-4 (AQP4) is a ~34 kDa protein. Forms a water-specific channel. Plays an important role in brain water homeostasis. It is involved in glymphatic solute transport and is required for a normal rate of water exchange across the blood brain interface. Required for normal levels of cerebrospinal fluid influx into the brain cortex and parenchyma along paravascular spaces that surround penetrating arteries, and for normal drainage of interstitial fluid along paravenous drainage pathways. Thereby, it is required for normal clearance of solutes from the brain interstitial fluid, including soluble beta-amyloid peptides derived from APP.

1. Ho, JD. et al. (2009) Proceedings of the National Academy of Sciences of the United States of America 106, 7437-42. PMID: 19383790
2. Yang, B. et al. (1995) The Journal of biological chemistry 270, 22907-13. PMID: 7559426
3. Misaka, T. et al. (1996) FEBS letters 381, 208-12. PMID: 8601457
4. Passchier, EMJ. et al. (2023) Brain : a journal of neurology 146, 3444-3454. PMID: 37143309
NoteFor research use only.
Isotype ControlMouse IgG2a (Fc Silence) Recombinant Isotype Control (MOPC 173) (MF533023)
图片
  • SDS-PAGE

    SDS-PAGE for Anti-Human AQP4/Aquaporin-4 Antibody (SAA1755).

参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量,自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项,自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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