Anti-ORF7a/Protein U122 Polyclonal Antibody (VK586014)

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概述
图片
参考文献
产品说明书

概述

货号

VK586014

品牌

abinScience

描述

Anti-ORF7a/Protein U122 Polyclonal Antibody (VK586014) is a rabbit polyclonal antibody detecting ORF7a protein in ELISA, IHC, WB.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

种属反应性

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)

应用

ELISA, IHC, WB

宿主

Rabbit

同种型

IgG

克隆类型

Polyclonal

免疫原

E. coli - derived recombinant SARS-CoV-2 ORF7a/Protein U122 (Glu16-Tyr97).

靶标

ORF7a protein, ORF7a, Accessory protein 7a, Protein U122, Protein X4, 7a

纯化方式

Purified by antigen affinity column.

Accession号

P0DTC7

状态

Liquid

保存溶液

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

背景

ORF7a protein (Protein U122) is a ~13 kDa protein. Plays a role as antagonist of host tetherin (BST2), disrupting its antiviral effect. Acts by binding to BST2 and sequestering it to perinuclear region, thereby preventing its antiviral function at cell membrane. May specifically downregulate MHC-I allele HLA-A*02:01 (HLA-A2).

1. Martin-Sancho, L. et al. (2021) Molecular cell 81, 2656-2668.e8. PMID: 33930332

2. Arshad, N. et al. (2023) Proceedings of the National Academy of Sciences of the United States of America 120, e2208525120. PMID: 36574644

Note

For research use only.

图片

参考文献

产品说明书

Anti-ORF7a/Protein U122 Polyclonal Antibody.pdf

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

浓度

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-ORF7a/Protein U122 Polyclonal Antibody (VK586014)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-ORF7a/Protein U122 Polyclonal Antibody (VK586014)

概述

图片

参考文献

产品说明书

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