Anti-Mouse Glypican 3 Recombinant Antibody (7C8) (MW310013)

价格:

规格：

50ug
100ug
1mg

数量：

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概述
图片
参考文献
产品说明书

MW310013

abinScience

种属反应性

Mouse

Blocking, ELISA, FCM

经测试应用

GPC3, MXR7, GTR2-2, Glypican-3, Intestinal protein OCI-5, OCI5

内毒素水平

Please contact with the lab for this information.

>95% as determined by SDS-PAGE.

Protein A/G purified from cell culture supernatant.

Accession号

Q8CFZ4

Anti-Mouse GPC3 Antibody (7C8) (abinScience Cat# MW310013, RRID:AB_3725638)

Liquid

0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:2000-1:20000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Glypican-3 (GPC3/Glypican 3) is a ~65 kDa protein. Cell surface proteoglycan. Negatively regulates the hedgehog signaling pathway when attached via the GPI-anchor to the cell surface by competing with the hedgehog receptor PTC1 for binding to hedgehog proteins. Binding to the hedgehog protein SHH triggers internalization of the complex by endocytosis and its subsequent lysosomal degradation. Positively regulates the canonical Wnt signaling pathway by binding to the Wnt receptor Frizzled and stimulating the binding of the Frizzled receptor to Wnt ligands. Positively regulates the non-canonical Wnt signaling pathway.

1. Capurro, MI. et al. (2008) Developmental cell 14, 700-11. PMID: 18477453

2. Bhave, VS. et al. (2013) The American journal of pathology 183, 153-9. PMID: 23665349

3. Song, HH. et al. (2005) The Journal of biological chemistry 280, 2116-25. PMID: 15537637

4. Paine-Saunders, S. et al. (2000) Developmental biology 225, 179-87. PMID: 10964473

5. Grisaru, S. et al. (2001) Developmental biology 231, 31-46. PMID: 11180950

6. Ng, A. et al. (2009) Developmental biology 335, 208-15. PMID: 19733558

For research use only.

SDS-PAGE

SDS-PAGE for Anti-Mouse GPC3 Antibody (7C8).
Western blot

Lane 1: HepG2 cell lysate

产品说明书

Anti-Mouse Glypican 3 Recombinant Antibody (7C8).pdf

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

分子量 *

g/mol

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

C₁ (起始浓度)

V₁ (起始体积)

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Mouse Glypican 3 Recombinant Antibody (7C8) (MW310013)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Mouse Glypican 3 Recombinant Antibody (7C8) (MW310013)

概述

图片

参考文献

产品说明书

相关产品推荐

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