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Anti-Human TYRP1 Recombinant Antibody (TA99) (HB884013)

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规格:
  • 50ug
  • 100ug
  • 1mg
数量:
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概述
货号HB884013
品牌abinScience
种属反应性Human, Mouse, Rat
应用IF, WB
宿主Mouse
克隆类型Monoclonal
同种型IgG2a, kappa
克隆号TA99
靶标5, 6-dihydroxyindole-2-carboxylic acid oxidase, Glycoprotein 75, CAS2, TYRP1, TRP-1, TYRRP, TRP1, Catalase B, TYRP, Melanoma antigen gp75, TRP, DHICA oxidase, Tyrosinase-related protein 1
内毒素水平Please contact with the lab for this information.
纯度>95% as determined by SDS-PAGE.
纯化方式Protein A/G purified from cell culture supernatant.
Accession号P17643
RRIDAnti-Human TYRP1 Antibody (TA99) (abinScience Cat# HB884013, RRID:AB_3725672)
状态Liquid
保存溶液 0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息
应用方法 稀释比例
WB 1:500-1:2000
稳定性和存储Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
背景

5,6-dihydroxyindole-2-carboxylic acid oxidase (TYRP1) is a ~60 kDa protein. Plays a role in melanin biosynthesis. Catalyzes the oxidation of 5,6-dihydroxyindole-2-carboxylic acid (DHICA) into indole-5,6-quinone-2-carboxylic acid in the presence of bound Cu(2+) ions, but not in the presence of Zn(2+). May regulate or influence the type of melanin synthesized. Also to a lower extent, capable of hydroxylating tyrosine and producing melanin.

1. Rooryck, C. et al. (2006) Pigment cell research 19, 239-42. PMID: 16704458
2. Kenny, EE. et al. (2012) Science (New York, N.Y.) 336, 554. PMID: 22556244
3. Simeonov, DR. et al. (2013) Human mutation 34, 827-35. PMID: 23504663
4. Lai, X. et al. (2017) Angewandte Chemie (International ed. in English) 56, 9812-9815. PMID: 28661582
NoteFor research use only.
Isotype ControlMouse IgG2a, kappa Recombinant Isotype Control Antibody (MOPC-173) (MF533507)
Mouse IgG2a Recombinant Isotype Control Antibody (S43.10) (MF533307)
图片
  • SDS-PAGE

    SDS-PAGE for Anti-Human TYRP1 Antibody (TA99).

参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量,自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项,自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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