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Anti-Phospho-STAT3 (pY705) Recombinant Antibody (SAA0302) (HW708013)

价格:
规格:
  • 50ug
  • 100ug
  • 1mg
数量:
  • 概述

  • 图片

  • 参考文献

  • 产品说明书

概述
货号HW708013
品牌abinScience
种属反应性Human, Mouse
应用ELISA, IP, WB
同种型IgG2a, kappa
克隆号SAA0302
靶标Signal transducer and activator of transcription 3, APRF, STAT3, Acute-phase response factor
内毒素水平Please contact with the lab for this information.
纯度>95% as determined by SDS-PAGE.
纯化方式Protein A/G purified from cell culture supernatant.
Accession号P40763
RRIDAnti-Phospho-STAT3 (pY705) Antibody (SAA0302) (abinScience Cat# HW708013, RRID:AB_3725763)
状态Liquid
保存溶液 0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息
应用方法 稀释比例
ELISA 1:2000-1:20000
WB 1:500-1:2000
稳定性和存储Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
背景

Signal transducer and activator of transcription 3 (p-STAT3) is a ~88 kDa protein. Signal transducer and transcription activator that mediates cellular responses to interleukins, KITLG/SCF, LEP and other growth factors. Once activated, recruits coactivators, such as NCOA1 or MED1, to the promoter region of the target gene. May mediate cellular responses to activated FGFR1, FGFR2, FGFR3 and FGFR4. Upon activation of IL6ST/gp130 signaling by interleukin-6 (IL6), binds to the IL6-responsive elements identified in the promoters of various acute-phase protein genes. Activated by IL31 through IL31RA.

1. Tsai, YT. et al. (2000) Molecular and cellular biology 20, 2043-54. PMID: 10688651
2. Yamamoto, T. et al. (2002) Biochemical and biophysical research communications 297, 811-7. PMID: 12359225
3. Shao, H. et al. (2003) Cancer research 63, 3923-30. PMID: 12873986
4. Dreuw, A. et al. (2004) The Journal of biological chemistry 279, 36112-20. PMID: 15194700
5. Yuan, ZL. et al. (2005) Science (New York, N.Y.) 307, 269-73. PMID: 15653507
6. Ray, S. et al. (2005) Gastroenterology 129, 1616-32. PMID: 16285960
7. Saxena, NK. et al. (2007) The Journal of biological chemistry 282, 13316-25. PMID: 17344214
8. Jiang, H. et al. (2008) Biochemical and biophysical research communications 368, 1-5. PMID: 18242580
9. Hou, T. et al. (2008) The Journal of biological chemistry 283, 30725-34. PMID: 18782771
10. Gao, X. et al. (2012) Molecular cell 45, 598-609. PMID: 22306293
NoteFor research use only.
图片
  • SDS-PAGE

    SDS-PAGE for Anti-Phospho-STAT3 (pY705) Antibody (SAA0302)

参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量,自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项,自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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